FBXO25 and BRME1

Data Source:
BioGRID (enzymatic study)

		FBXO25	BRME1
Description		F-box protein 25	break repair meiotic recombinase recruitment factor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleolus SCF Ubiquitin Ligase Complex	Cellular_component Chromosome
	Molecular Function	Actin Binding Ubiquitin-protein Transferase Activity	Molecular_function Protein Binding
	Biological Process	Protein Ubiquitination	Multicellular Organism Development Spermatogenesis Double-strand Break Repair Involved In Meiotic Recombination
Pathways
Drugs
Diseases
GWAS		Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952)
Interacting Genes		82 interacting genes: ANKRD13A APLF AXL BMX BRME1 C7orf50 CDK5RAP2 CDK9 CENPB CUL1 CXXC4 DCX DDX42 DEPTOR DNAJB2 DNAJC8 DYRK3 DYRK4 EGFR EID3 EIF4E2 ELK1 EPN1 FKBP3 G3BP1 GRK2 GTF2B GTF2IRD2 HIP1 HMCES HP1BP3 IL21 ILRUN ING3 IRS1 JHY KDR KRT8 LMCD1 LUC7L MAT2B NKX2-5 NSRP1 NUAK1 ODF2 ORC4 PADI4 PAK4 PCK1 PDGFRA PIP4K2C PPID PPP1R8 PRKCA PRKG2 PRR15 PRRG1 PSMD4 RABEP2 RBM8A RHBDD1 RIOK3 RPAP3 RPS10 RPS6KB2 SAMHD1 SERBP1 SKP1 STAC SYTL2 TBX5 TCEAL2 TCEANC TCP10L TMA7 TNIP2 TRUB1 TWF1 UBE2D3 UBQLN1 UBQLN2 WDSUB1	32 interacting genes: ADAMTSL4 AIMP2 APP C19orf25 CENPQ COPS4 CTNNAL1 CYSRT1 EWSR1 FAM9B FBXO25 GPS2 HAUS3 HOMER1 IKBKG KRT31 KRT34 KRT38 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 NBPF19 NOTCH2NLA PSMA6 RABL6 RUNX1T1 STXBP1 TRIM23 TSC22D3 VCL
Entrez ID		26260	79173
HPRD ID		16439	14415
Ensembl ID		ENSG00000147364	ENSG00000132016
Uniprot IDs		A0A024QZ88 Q8TCJ0	Q0VDD7
PDB IDs
Enriched GO Terms of Interacting Partners?
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