RAI14 and FEZ1

Data Source:
BioGRID (two hybrid, pull down)
HPRD (two hybrid, in vitro)

		RAI14	FEZ1
Description		retinoic acid induced 14	fasciculation and elongation protein zeta 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleoplasm Cytosol Cytoskeleton Cell Cortex Cell Junction	Cytoplasm Mitochondrion Golgi Apparatus Centrosome Microtubule Plasma Membrane Axon Dendrite Growth Cone Neuronal Cell Body
	Molecular Function	Actin Binding Protein Binding	Protein Kinase C Binding Protein Binding Gamma-tubulin Binding Protein N-terminus Binding
	Biological Process	Spermatogenesis Cell Differentiation	Cell Adhesion Nervous System Development Axon Guidance Positive Regulation Of Neuron Projection Development Hippocampus Development Establishment Of Cell Polarity Positive Regulation Of Neuron Differentiation Establishment Of Mitochondrion Localization Positive Regulation Of Anterograde Axonal Transport Of Mitochondrion Mitochondrion Morphogenesis Cellular Response To Growth Factor Stimulus Negative Regulation Of Autophagosome Assembly
Pathways
Drugs
Diseases
GWAS		Age-related cognitive decline (attention/processing speed) (slope of z-scores) ( 30954325) Blood urea nitrogen levels ( 31152163) Chronic kidney disease ( 31152163) Creatinine levels ( 29403010) Daytime sleep phenotypes ( 27126917) Estimated glomerular filtration rate ( 31152163 31015462 31451708 30604766) Estimated glomerular filtration rate in diabetes ( 31451708) Glomerular filtration rate ( 29403010) Hematocrit ( 32888494) Hemoglobin ( 32888494) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) LDL cholesterol levels ( 32203549) Left ventricular mass ( 19454037) Platelet count ( 32888494) Red blood cell count ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Serum uric acid levels ( 30993211) Urate levels ( 31578528) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)	Breast cancer (survival) ( 25890600) Schizophrenia ( 22688191 23894747)
Interacting Genes		7 interacting genes: FEZ1 FEZ2 ITSN1 RND1 YWHAB YWHAG YWHAQ	57 interacting genes: BARD1 BORA BRD1 C8orf33 CCL7 CEP126 CIB1 CLASP2 COL9A2 CSTF2 DIS3L2 DISC1 DNAAF5 DRAP1 FEZ2 GEMIN7 GTF2F1 HAP1 HTATSF1 HTT IMMT LRIF1 MEST NBR1 NDUFB9 NEK1 OLFML3 P4HB PAM16 PDCD7 PPP4R3B PRKCZ PTH PTN PTPRS RAB3GAP1 RAB3GAP2 RAI14 RIF1 SAP30L SCOC SERPINH1 SMARCD1 SMC3 STAR TAC3 TAF1D TAF9 TBC1D25 TEDC2 TLK2 TOMM20 TTR TXNDC9 UBE4B WWC1 ZNF251
Entrez ID		26064	9638
HPRD ID		09416	09212
Ensembl ID		ENSG00000039560	ENSG00000149557
Uniprot IDs		Q9P0K7	Q99689
PDB IDs
Enriched GO Terms of Interacting Partners?
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