FEZ1 and TBC1D25

Data Source:
HPRD (two hybrid)

		FEZ1	TBC1D25
Description		fasciculation and elongation protein zeta 1	TBC1 domain family member 25
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Golgi Apparatus Centrosome Microtubule Plasma Membrane Axon Dendrite Growth Cone Neuronal Cell Body	Autophagosome Cytoplasmic Vesicle
	Molecular Function	Protein Kinase C Binding Protein Binding Gamma-tubulin Binding Protein N-terminus Binding	GTPase Activator Activity Protein Binding
	Biological Process	Cell Adhesion Nervous System Development Axon Guidance Positive Regulation Of Neuron Projection Development Hippocampus Development Establishment Of Cell Polarity Positive Regulation Of Neuron Differentiation Establishment Of Mitochondrion Localization Positive Regulation Of Anterograde Axonal Transport Of Mitochondrion Mitochondrion Morphogenesis Cellular Response To Growth Factor Stimulus Negative Regulation Of Autophagosome Assembly	Intracellular Protein Transport Autophagy Activation Of GTPase Activity Regulation Of Autophagosome Maturation
Pathways			TBC/RABGAPs
Drugs
Diseases
GWAS		Breast cancer (survival) ( 25890600) Schizophrenia ( 22688191 23894747)
Interacting Genes		57 interacting genes: BARD1 BORA BRD1 C8orf33 CCL7 CEP126 CIB1 CLASP2 COL9A2 CSTF2 DIS3L2 DISC1 DNAAF5 DRAP1 FEZ2 GEMIN7 GTF2F1 HAP1 HTATSF1 HTT IMMT LRIF1 MEST NBR1 NDUFB9 NEK1 OLFML3 P4HB PAM16 PDCD7 PPP4R3B PRKCZ PTH PTN PTPRS RAB3GAP1 RAB3GAP2 RAI14 RIF1 SAP30L SCOC SERPINH1 SMARCD1 SMC3 STAR TAC3 TAF1D TAF9 TBC1D25 TEDC2 TLK2 TOMM20 TTR TXNDC9 UBE4B WWC1 ZNF251	16 interacting genes: FAM9B FEZ1 FEZ2 GABARAP GABARAPL1 GABARAPL2 KCNIP1 LARP1B LGALS14 LMNTD2 MAP1LC3A MAP1LC3B MAP1LC3C RAB2A RUSC1 TRIML2
Entrez ID		9638	4943
HPRD ID		09212	08948
Ensembl ID		ENSG00000149557	ENSG00000068354
Uniprot IDs		Q99689	B4DF03 Q3MII6
PDB IDs
Enriched GO Terms of Interacting Partners?
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