FEZ1 and SCOC

Data Source:
BioGRID (affinity chromatography technology, two hybrid)
HPRD (two hybrid)

		FEZ1	SCOC
Description		fasciculation and elongation protein zeta 1	short coiled-coil protein
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Golgi Apparatus Centrosome Microtubule Plasma Membrane Axon Dendrite Growth Cone Neuronal Cell Body	Golgi Membrane Nucleoplasm Endosome Golgi Apparatus Trans-Golgi Network Cytosol
	Molecular Function	Protein Kinase C Binding Protein Binding Gamma-tubulin Binding Protein N-terminus Binding	Protein Binding
	Biological Process	Cell Adhesion Nervous System Development Axon Guidance Positive Regulation Of Neuron Projection Development Hippocampus Development Establishment Of Cell Polarity Positive Regulation Of Neuron Differentiation Establishment Of Mitochondrion Localization Positive Regulation Of Anterograde Axonal Transport Of Mitochondrion Mitochondrion Morphogenesis Cellular Response To Growth Factor Stimulus Negative Regulation Of Autophagosome Assembly	Positive Regulation Of Macroautophagy Regulation Of Protein Complex Stability
Pathways			Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Breast cancer (survival) ( 25890600) Schizophrenia ( 22688191 23894747)	Malaria ( 31844061) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		57 interacting genes: BARD1 BORA BRD1 C8orf33 CCL7 CEP126 CIB1 CLASP2 COL9A2 CSTF2 DIS3L2 DISC1 DNAAF5 DRAP1 FEZ2 GEMIN7 GTF2F1 HAP1 HTATSF1 HTT IMMT LRIF1 MEST NBR1 NDUFB9 NEK1 OLFML3 P4HB PAM16 PDCD7 PPP4R3B PRKCZ PTH PTN PTPRS RAB3GAP1 RAB3GAP2 RAI14 RIF1 SAP30L SCOC SERPINH1 SMARCD1 SMC3 STAR TAC3 TAF1D TAF9 TBC1D25 TEDC2 TLK2 TOMM20 TTR TXNDC9 UBE4B WWC1 ZNF251	16 interacting genes: ARL1 BFSP2 C21orf91 DDIT4L DOK5 FEZ1 FEZ2 ITSN1 KIFC3 KRT40 MAPK8 PSMC5 SCHIP1 SIKE1 TCF4 TRAPPC6A
Entrez ID		9638	60592
HPRD ID		09212	18027
Ensembl ID		ENSG00000149557	ENSG00000153130
Uniprot IDs		Q99689	Q9UIL1
PDB IDs			4BWD
Enriched GO Terms of Interacting Partners?
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