RAI14 and RND1

Data Source:
BioGRID (two hybrid)

		RAI14	RND1
Description		retinoic acid induced 14	Rho family GTPase 1
Image		No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleoplasm Cytosol Cytoskeleton Cell Cortex Cell Junction	Cytosol Cytoskeleton Plasma Membrane Adherens Junction Cell Cortex Actin Cytoskeleton Cytoplasmic Vesicle Cell Projection Intracellular Membrane-bounded Organelle
	Molecular Function	Actin Binding Protein Binding	GTPase Activity Signaling Receptor Binding Protein Binding GTP Binding Protein Kinase Binding
	Biological Process	Spermatogenesis Cell Differentiation	Actin Filament Organization Negative Regulation Of Cell Adhesion Establishment Or Maintenance Of Cell Polarity Small GTPase Mediated Signal Transduction Regulation Of Cell Shape Neuron Remodeling Cell Migration Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization
Pathways			SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion Sema4D mediated inhibition of cell attachment and migration Sema4D induced cell migration and growth-cone collapse
Drugs
Diseases
GWAS		Age-related cognitive decline (attention/processing speed) (slope of z-scores) ( 30954325) Blood urea nitrogen levels ( 31152163) Chronic kidney disease ( 31152163) Creatinine levels ( 29403010) Daytime sleep phenotypes ( 27126917) Estimated glomerular filtration rate ( 31152163 31015462 31451708 30604766) Estimated glomerular filtration rate in diabetes ( 31451708) Glomerular filtration rate ( 29403010) Hematocrit ( 32888494) Hemoglobin ( 32888494) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) LDL cholesterol levels ( 32203549) Left ventricular mass ( 19454037) Platelet count ( 32888494) Red blood cell count ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Serum uric acid levels ( 30993211) Urate levels ( 31578528) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)	Bipolar disorder ( 21926972)
Interacting Genes		7 interacting genes: FEZ1 FEZ2 ITSN1 RND1 YWHAB YWHAG YWHAQ	23 interacting genes: ARFIP2 ARHGAP5 CCNI COPS2 CREB3L2 EEF1A1 FRS2 FRS3 GPX8 GRB7 ID3 MYH7 MYOM3 MYZAP NEDD1 PAIP1 PDE6D PLXNA1 PLXNB1 PLXNB2 RAI14 UBXN11 ZNF212
Entrez ID		26064	27289
HPRD ID		09416	12357
Ensembl ID		ENSG00000039560	ENSG00000172602
Uniprot IDs		Q9P0K7	Q92730
PDB IDs			2CLS 2REX 3Q3J
Enriched GO Terms of Interacting Partners?
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