GLCE and BCAR3

Data Source:
BioGRID (two hybrid)

		GLCE	BCAR3
Description		glucuronic acid epimerase	BCAR3 adaptor protein, NSP family member
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GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Integral Component Of Membrane	Cytoplasm Focal Adhesion Membrane
	Molecular Function	Calcium Ion Binding Racemase And Epimerase Activity, Acting On Carbohydrates And Derivatives Protein Homodimerization Activity Heparosan-N-sulfate-glucuronate 5-epimerase Activity	Phosphotyrosine Residue Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding Kinase Binding
	Biological Process	Heparan Sulfate Proteoglycan Biosynthetic Process Heparin Biosynthetic Process	Lens Morphogenesis In Camera-type Eye Signal Transduction Small GTPase Mediated Signal Transduction Insulin Receptor Signaling Pathway Positive Regulation Of Peptidyl-serine Phosphorylation Response To Drug Positive Regulation Of MAPK Cascade Positive Regulation Of GTPase Activity Positive Regulation Of DNA Replication Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Endothelin Receptor Signaling Pathway
Pathways		HS-GAG biosynthesis
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488)	Alzheimer's disease progression score ( 29860282) Blood urea nitrogen levels ( 31152163) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Estimated glomerular filtration rate ( 31152163) Liver fibrosis (total hepatic collagen content) ( 32953199) Major depressive disorder ( 27777418) Systolic blood pressure ( 30224653)
Interacting Genes		11 interacting genes: BAG4 BCAR3 CASP8 ERBB2 ESR1 FBXO7 FGFR2 FGFR4 PAX2 PPM1D RB1CC1	38 interacting genes: AGR3 AP1M1 APP ATAD2 BAP1 BEX1 BEX2 CASZ1 CCDC57 CCL5 CST6 DKK3 EGFR EPSTI1 ERBB2 ERBB3 ERBB4 ERRFI1 GAB1 GAS8 GLCE GREB1 HOXC6 KIT KPNA1 MET MTA3 NEDD9 NSD3 OSGIN1 PDLIM2 PRDM14 PSMC3IP RPRD1A SERPINB5 THRSP UBASH3A VPS45
Entrez ID		26035	8412
HPRD ID		07020	05268
Ensembl ID		ENSG00000138604	ENSG00000137936
Uniprot IDs		O94923	A0A384MTS3 B3KNL6 B3KP06 O75815
PDB IDs		6HZZ 6I01 6I02	3T6A
Enriched GO Terms of Interacting Partners?
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