GLCE and RB1CC1

Data Source:
BioGRID (two hybrid)

		GLCE	RB1CC1
Description		glucuronic acid epimerase	RB1 inducible coiled-coil 1
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GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Integral Component Of Membrane	Phagophore Assembly Site Autophagosome Membrane Lysosome Endoplasmic Reticulum Membrane Cytosol Extrinsic Component Of Membrane Nuclear Membrane Phagophore Assembly Site Membrane Atg1/ULK1 Kinase Complex
	Molecular Function	Calcium Ion Binding Racemase And Epimerase Activity, Acting On Carbohydrates And Derivatives Protein Homodimerization Activity Heparosan-N-sulfate-glucuronate 5-epimerase Activity	Protein Binding Protein Kinase Binding Molecular Adaptor Activity
	Biological Process	Heparan Sulfate Proteoglycan Biosynthetic Process Heparin Biosynthetic Process	Autophagosome Assembly Autophagy Of Mitochondrion Liver Development Positive Regulation Of Protein Phosphorylation Autophagy Cell Cycle Heart Development Macroautophagy Regulation Of Macroautophagy Autophagy Of Peroxisome Piecemeal Microautophagy Of The Nucleus Positive Regulation Of Cell Size Positive Regulation Of JNK Cascade Reticulophagy Glycophagy Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		HS-GAG biosynthesis	Macroautophagy
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488)	Body size at age 10 ( 32376654) Immunoglobulin light chain (AL) amyloidosis (liver involvement) ( 28679651) Mitochondrial DNA copy number (white blood cells) ( 30704525) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		11 interacting genes: BAG4 BCAR3 CASP8 ERBB2 ESR1 FBXO7 FGFR2 FGFR4 PAX2 PPM1D RB1CC1	33 interacting genes: AZI2 BAP1 BLID COP1 EPSTI1 ERRFI1 EXOC1 GABARAP GABARAPL1 GABARAPL2 GLCE GREB1 HBP1 IL13RA2 IL24 ITIH5 LYPD3 MADD MRC2 NSD3 PSMC3IP PTK2 PTK2B RNF20 SYN1 TAX1BP1 TBKBP1 THRSP UBC UMPS VHL VPS45 WIF1
Entrez ID		26035	9821
HPRD ID		07020	06019
Ensembl ID		ENSG00000138604	ENSG00000023287
Uniprot IDs		O94923	Q8TDY2
PDB IDs		6HZZ 6I01 6I02	6DCE 6GMA
Enriched GO Terms of Interacting Partners?
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