BCAR3 and BEX1

Data Source:
BioGRID (two hybrid)

		BCAR3	BEX1
Description		BCAR3 adaptor protein, NSP family member	brain expressed X-linked 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Focal Adhesion Membrane	Nucleus Transcription Regulator Complex Cytoplasm
	Molecular Function	Phosphotyrosine Residue Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding Kinase Binding	RNA Polymerase II Activating Transcription Factor Binding Signaling Receptor Binding Protein Binding
	Biological Process	Lens Morphogenesis In Camera-type Eye Signal Transduction Small GTPase Mediated Signal Transduction Insulin Receptor Signaling Pathway Positive Regulation Of Peptidyl-serine Phosphorylation Response To Drug Positive Regulation Of MAPK Cascade Positive Regulation Of GTPase Activity Positive Regulation Of DNA Replication Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Endothelin Receptor Signaling Pathway	Signal Transduction Nervous System Development Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-binding Transcription Factor Activity
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease progression score ( 29860282) Blood urea nitrogen levels ( 31152163) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Estimated glomerular filtration rate ( 31152163) Liver fibrosis (total hepatic collagen content) ( 32953199) Major depressive disorder ( 27777418) Systolic blood pressure ( 30224653)
Interacting Genes		38 interacting genes: AGR3 AP1M1 APP ATAD2 BAP1 BEX1 BEX2 CASZ1 CCDC57 CCL5 CST6 DKK3 EGFR EPSTI1 ERBB2 ERBB3 ERBB4 ERRFI1 GAB1 GAS8 GLCE GREB1 HOXC6 KIT KPNA1 MET MTA3 NEDD9 NSD3 OSGIN1 PDLIM2 PRDM14 PSMC3IP RPRD1A SERPINB5 THRSP UBASH3A VPS45	31 interacting genes: AKT1 BAG4 BCAR3 CASP8 CHEK2 CNOT2 CTAG1A CTAG1B CYSRT1 FBXW7 FGFR2 FZR1 GSK3B KLHL20 KRT31 KRT34 MAGEA2 MAGEA2B MDFI MEOX2 NGFR OMP OTP PAX2 PICK1 PIK3CA PTEN PTPN11 SMAD4 TENM1 TEX11
Entrez ID		8412	55859
HPRD ID		05268	06460
Ensembl ID		ENSG00000137936	ENSG00000133169
Uniprot IDs		A0A384MTS3 B3KNL6 B3KP06 O75815	Q9HBH7
PDB IDs		3T6A
Enriched GO Terms of Interacting Partners?
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