Description |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon |
MDM4 regulator of p53 |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
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- Breast cancer ( 23535733 27117709)
- Breast cancer (estrogen-receptor negative) ( 27117709 29058716)
- Breast cancer (estrogen-receptor negative, progesterone-receptor negative, and human epidermal growth factor-receptor negative) ( 24325915)
- Breast Cancer in BRCA1 mutation carriers ( 23544013)
- Cognitive performance ( 19734545)
- Diastolic blood pressure ( 27618452 30578418)
- Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
- Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
- Eosinophil counts ( 32888494)
- Eosinophil percentage of white cells ( 32888494)
- Fish- and plant-related diet ( 32066663)
- Glioma ( 28346443)
- Levodopa wearing off effect (time symptoms uncontrolled) in Parkinson's disease (response to zonisamide) ( 32355309)
- Non-glioblastoma glioma ( 28346443)
- Oily fish consumption ( 32066663)
- Pork consumption ( 32066663)
- Prostate cancer ( 23535732)
- Regular attendance at a religious group ( 29970889)
- Systolic blood pressure ( 27618452)
- Type 2 diabetes ( 32499647)
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Interacting Genes |
147 interacting genes:
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ABL1
ACD
AKAP13
AKAP9
ANKHD1-EIF4EBP3
ANKZF1
ARHGEF2
ARHGEF28
ATP6V0B
ATXN1
BAD
BCR
BEX3
CALM1
CAP2
CASK
CASP3
CCDC125
CCR9
CDC25A
CDC25B
CDK11B
CDK14
CDK16
CDKN1B
CEP131
CEP95
CGNL1
CHAF1A
CHST11
CYSLTR2
DDX54
DISC1
DYRK1A
ENKD1
EXO1
FAM13B
FAM53C
FGF12
FHL1
FTH1
GAPDH
GPRIN2
GRAP2
GSTA1
GSTM3
GTF2B
HDAC4
HDAC5
HIVEP2
HNRNPC
HSF1
HSPB1
IGF1R
IL7R
ING1
IRAG2
IRS1
IRS2
ITPRID2
KANK1
KCNH2
KCNK15
KCNK3
KCNK9
KIAA0232
KIF1C
KLC4
KRT18
LCP2
MAGEB4
MAP3K1
MAP3K10
MAP3K2
MAP3K3
MAP3K5
MAPK7
MCM10
MDM4
METAP2
MSL2
MST1R
MT-CO2
MYH10
NAF1
NCOR2
NDEL1
NIN
PAPOLA
PARD3B
PCM1
PIMREG
PNLIP
POT1
PRC1
PRDX6
PRKCG
RAB11FIP2
RAF1
RAP1GAP2
RASAL3
RASGRF1
RBIS
RBM14
REM1
RGS3
RIN1
RPA2
RPGR
RXFP3
SAMSN1
SH3BP4
SLC8A1
SLC8A2
SLC8A3
SMAGP
SNAPIN
SNCA
SNF8
SORBS2
SRC
SYN2
TAF7
TAZ
TBC1D3F
TBP
TCEANC
TFDP2
TGFB1
TLK1
TNFAIP3
TOP2A
TSC1
TSC2
UBE3A
USP43
VIM
WNK1
WWTR1
YWHAB
YWHAG
YWHAH
YWHAQ
YWHAZ
ZC3HC1
ZNF839
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63 interacting genes:
AKT1
APP
ARF1
ATM
BECN1
C1orf109
CAPN7
CASP3
CBLC
CD160
CD44
CDK1
CDK4
CDKN2A
CDKN2B
CHEK1
CHEK2
CSNK1A1
E2F1
EP300
EPHA2
FGFR4
GLIS2
HGF
LATS2
LRSAM1
MAGEA1
MAP2K5
MDM2
MKRN3
MNAT1
NAA10
NF2
PELI1
PRKAA1
RAD54B
RB1
RNF115
S100B
SFN
SMAD3
SMAD4
SMARCA2
TP53
TP63
TP73
TRIM46
TRIM55
UBC
UBE2D1
UBE2D2
UBE2D3
USP7
VPS26C
WDR5
YWHAB
YWHAE
YWHAG
YWHAH
YWHAQ
YWHAZ
ZKSCAN3
ZKSCAN4
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Entrez ID |
7531 |
4194 |
HPRD ID |
05457 |
04082 |
Ensembl ID |
ENSG00000108953
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ENSG00000198625
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Uniprot IDs |
P62258
V9HW98
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A0A087WTR9
A0A087WUE3
A0A087WZ58
O15151
Q59FS6
Q68DC0
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PDB IDs |
2BR9
3UAL
3UBW
6EIH
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2CR8
2MWY
2N06
2N0U
2N0W
2N14
2VJE
2VJF
2VYR
3DAB
3EQY
3FDO
3FE7
3FEA
3JZO
3JZP
3JZQ
3LBJ
3MQR
3U15
4RXZ
5MNJ
5UML
5VK1
6Q9Q
6Q9S
6Q9U
6Q9W
6Q9Y
7C3Q
7C3Y
7C44
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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