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YWHAE and KRT18
Data Source:
HPRD
(in vivo)
YWHAE
KRT18
Description
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
keratin 18
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Mitochondrion
Cytosol
Kinesin Complex
Plasma Membrane
Focal Adhesion
Membrane
Melanosome
Extracellular Exosome
Central Region Of Growth Cone
Glutamatergic Synapse
Nucleolus
Cytoplasm
Microtubule Organizing Center
Cytosol
Intermediate Filament
Adherens Junction
External Side Of Plasma Membrane
Protein-containing Complex
Centriolar Satellite
Keratin Filament
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Molecular Function
RNA Binding
Calcium Channel Regulator Activity
Protein Binding
Potassium Channel Regulator Activity
Enzyme Binding
MHC Class II Protein Complex Binding
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Histone Deacetylase Binding
Ion Channel Binding
Cadherin Binding
Protein Heterodimerization Activity
Phosphoserine Residue Binding
Phosphoprotein Binding
Scaffold Protein Binding
RNA Binding
Structural Molecule Activity
Protein Binding
Scaffold Protein Binding
Cadherin Binding Involved In Cell-cell Adhesion
Biological Process
G2/M Transition Of Mitotic Cell Cycle
MAPK Cascade
Regulation Of Heart Rate By Hormone
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Viral Process
Substantia Nigra Development
Protein Localization To Nucleus
Cellular Response To Heat
Hippo Signaling
Intracellular Signal Transduction
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Protein Export From Nucleus
Regulation Of Cytosolic Calcium Ion Concentration
Regulation Of Membrane Repolarization
Membrane Organization
Membrane Repolarization During Cardiac Muscle Cell Action Potential
Regulation Of Heart Rate By Cardiac Conduction
Ciliary Basal Body-plasma Membrane Docking
Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels
Regulation Of Cellular Response To Heat
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Regulation Of Potassium Ion Transmembrane Transporter Activity
Negative Regulation Of Calcium Ion Transmembrane Transporter Activity
Negative Regulation Of Peptidyl-serine Dephosphorylation
Negative Regulation Of Calcium Ion Export Across Plasma Membrane
Cell Cycle
Anatomical Structure Morphogenesis
Response To Fructose
Viral Process
Keratinization
Response To Nutrient Levels
Tumor Necrosis Factor-mediated Signaling Pathway
Golgi To Plasma Membrane CFTR Protein Transport
Negative Regulation Of Apoptotic Process
Intermediate Filament Cytoskeleton Organization
Cornification
Hepatocyte Differentiation
Mesenchymal Stem Cell Differentiation
Extrinsic Apoptotic Signaling Pathway
Hepatocyte Apoptotic Process
Cell-cell Adhesion
Cholangiocyte Apoptotic Process
Pathways
Activation of BAD and translocation to mitochondria
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Signaling by Hippo
NADE modulates death signalling
Regulation of PLK1 Activity at G2/M Transition
Regulation of HSF1-mediated heat shock response
HSF1 activation
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
RHO GTPases activate PKNs
TP53 Regulates Metabolic Genes
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
AURKA Activation by TPX2
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
RAB GEFs exchange GTP for GDP on RABs
Keratinization
Formation of the cornified envelope
Drugs
Fusicoccin
Phenethyl Isothiocyanate
Diseases
Lissencephaly (LIS); Miller-Dieker syndrome (MDLS)
GWAS
Atrial fibrillation (
30061737
)
High light scatter reticulocyte percentage of red cells (
32888494
)
Mean platelet volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Nicotine dependence symptom count (
25555482
)
Reaction time (
29844566
)
Schizophrenia (
28991256
30285260
)
Cleft lip with or without cleft palate (
28054174
)
Diffusing capacity of carbon monoxide (
30694715
)
Nonsyndromic cleft lip with cleft palate (
28232668
)
Interacting Genes
147 interacting genes:
-
ABL1
ACD
AKAP13
AKAP9
ANKHD1-EIF4EBP3
ANKZF1
ARHGEF2
ARHGEF28
ATP6V0B
ATXN1
BAD
BCR
BEX3
CALM1
CAP2
CASK
CASP3
CCDC125
CCR9
CDC25A
CDC25B
CDK11B
CDK14
CDK16
CDKN1B
CEP131
CEP95
CGNL1
CHAF1A
CHST11
CYSLTR2
DDX54
DISC1
DYRK1A
ENKD1
EXO1
FAM13B
FAM53C
FGF12
FHL1
FTH1
GAPDH
GPRIN2
GRAP2
GSTA1
GSTM3
GTF2B
HDAC4
HDAC5
HIVEP2
HNRNPC
HSF1
HSPB1
IGF1R
IL7R
ING1
IRAG2
IRS1
IRS2
ITPRID2
KANK1
KCNH2
KCNK15
KCNK3
KCNK9
KIAA0232
KIF1C
KLC4
KRT18
LCP2
MAGEB4
MAP3K1
MAP3K10
MAP3K2
MAP3K3
MAP3K5
MAPK7
MCM10
MDM4
METAP2
MSL2
MST1R
MT-CO2
MYH10
NAF1
NCOR2
NDEL1
NIN
PAPOLA
PARD3B
PCM1
PIMREG
PNLIP
POT1
PRC1
PRDX6
PRKCG
RAB11FIP2
RAF1
RAP1GAP2
RASAL3
RASGRF1
RBIS
RBM14
REM1
RGS3
RIN1
RPA2
RPGR
RXFP3
SAMSN1
SH3BP4
SLC8A1
SLC8A2
SLC8A3
SMAGP
SNAPIN
SNCA
SNF8
SORBS2
SRC
SYN2
TAF7
TAZ
TBC1D3F
TBP
TCEANC
TFDP2
TGFB1
TLK1
TNFAIP3
TOP2A
TSC1
TSC2
UBE3A
USP43
VIM
WNK1
WWTR1
YWHAB
YWHAG
YWHAH
YWHAQ
YWHAZ
ZC3HC1
ZNF839
91 interacting genes:
BBS1
BBS2
BBS4
BBS7
C1orf109
CAMK2A
CASP3
CASP6
CASP7
CASP8
CBL
CCDC146
CCDC85B
CCHCR1
CCNI
CDC5L
CDK1
COL17A1
DEDD
DNAJB6
EFHC1
EGFR
EP300
ESR1
EXOC8
FRAT1
GIT2
GOLGA2
GRN
HAUS1
HGS
HRAS
HSPA1A
HSPA4
HSPA5
HSPB1
IKBKG
KIFC3
KPNA2
KRT15
KRT5
KRT6A
KRT6C
KRT71
KRT72
KRT79
KRT8
KRT81
LDOC1
LINC01554
MAPK14
NEFL
NME7
ORC5
PDE4DIP
PIAS4
PKD1
PKP2
PKP3
PNN
POT1
PRKCA
PRKCE
PSTPIP2
RAF1
RCOR3
RHPN2
RPS6KA3
SERPINE1
SHC1
SMARCD1
SVIL
SYCE1
TCHP
TEKT4
TNFRSF1B
TRADD
TSG101
TUBG1
TUBGCP4
TXN2
TXNDC11
UPF2
USH2A
WBP2
YTHDC1
YWHAB
YWHAE
YWHAG
YWHAH
YWHAZ
Entrez ID
7531
3875
HPRD ID
05457
01020
Ensembl ID
ENSG00000108953
ENSG00000111057
Uniprot IDs
P62258
V9HW98
A0A024RAY2
P05783
PDB IDs
2BR9
3UAL
3UBW
6EIH
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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