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GAD2 and CMTM5
Data Source:
BioGRID
(two hybrid, two hybrid)
GAD2
CMTM5
Description
glutamate decarboxylase 2
CKLF like MARVEL transmembrane domain containing 5
Image
No pdb structure
GO Annotations
Cellular Component
Golgi Membrane
Cytosol
Plasma Membrane
Axon
Synaptic Vesicle Membrane
Anchored Component Of Membrane
Presynaptic Membrane
Perinuclear Region Of Cytoplasm
Inhibitory Synapse
Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane
Extracellular Space
Integral Component Of Membrane
Molecular Function
Glutamate Decarboxylase Activity
Protein Binding
Glutamate Binding
Pyridoxal Phosphate Binding
Protein-containing Complex Binding
Cytokine Activity
Protein Binding
Biological Process
Glutamate Decarboxylation To Succinate
Chemical Synaptic Transmission
Neurotransmitter Secretion
Neurotransmitter Biosynthetic Process
Response To Drug
Chemotaxis
Signal Transduction
Negative Regulation Of Myoblast Differentiation
Pathways
GABA synthesis
GABA synthesis, release, reuptake and degradation
MECP2 regulates transcription of genes involved in GABA signaling
Drugs
Pyridoxal phosphate
Glutamic acid
Diseases
GWAS
Lean body mass (
28552196
)
Interacting Genes
45 interacting genes:
ABHD5
AGTRAP
APOC2
APOC4
ARL13B
ARL6IP1
ARMC12
BSND
CACNG1
CMTM5
CPLX4
CYB561D1
DERL1
DERL3
DGAT2L6
DMKN
F10
FADS6
FAM114A2
FAM163A
GAD1
HIGD1C
LIME1
MAL2
MEST
MRM3
PBX3
PLIN3
PRKACA
PRKCE
RDH10
RHEX
RPRM
SCAMP1
SDR16C5
SEC22A
SMPD2
SPG21
SYCE2
SYNGR3
TMEM120B
TMEM128
TMEM159
TNFRSF10D
TSPAN33
131 interacting genes:
AACS
ABHD4
ACSF2
ACSM1
ALDH18A1
APOA1
APOA4
APOA5
AQP6
ARFIP1
ARFIP2
ARMC9
BIK
BNIP3
CAPNS2
CD160
CD40
CD79A
CLDN7
COQ8A
CPLX1
CPLX4
CREB3
CYP1A1
DDA1
DHRSX
ECPAS
ELOVL4
ERGIC3
FAM114A1
FARS2
FCGR2A
FCRL3
FERMT2
FFAR2
FNDC9
GAD1
GAD2
GJB1
GLTP
GOLGA2P10
GPX8
GTF3C1
HNRNPK
HSD17B13
JAGN1
JOSD2
KASH5
KCNJ6
KCNK5
KIR3DL3
LEUTX
LMNA
LMO2
LNX1
LRRC4C
LRRC59
MCEE
MCEMP1
MCFD2
MEOX2
MFF
MGST3
MIEF1
MRM1
MRRF
MTERF3
MTIF3
MYG1
NDRG4
NFU1
NTAQ1
PBX3
PCNA
PIMREG
PITPNC1
PLIN3
PNPO
POLL
PPIF
PPP2R3C
PSCA
PTPN9
RBFA
REEP2
RETREG3
RHBDD1
RMDN2
RNF185
RSRC2
RUSF1
SAR1A
SCARA5
SDCBP
SGCB
SH3GL1
SH3GLB1
SHMT2
SLC10A6
SLC18A2
SLC30A4
SLC35C2
SLC7A14
SNX1
SPATA8
SPG21
SSX3
SSX5
STING1
STOM
SUCLA2
SYNE4
SYT16
TBRG4
THAP4
TIMM44
TLCD4
TMED8
TMEM139
TMEM14B
TMEM35A
TMEM80
TMF1
TPD52L3
TSPAN31
TTPA
TUBB
TUFM
VARS2
ZNF391
ZNF599
Entrez ID
2572
116173
HPRD ID
11817
06986
Ensembl ID
ENSG00000136750
ENSG00000166091
Uniprot IDs
Q05329
Q5VZ30
Q96DZ9
PDB IDs
1ES0
2OKK
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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