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CMTM5 and FERMT2
Data Source:
BioGRID
(two hybrid)
CMTM5
FERMT2
Description
CKLF like MARVEL transmembrane domain containing 5
FERM domain containing kindlin 2
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Integral Component Of Membrane
Stress Fiber
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Plasma Membrane
Adherens Junction
Focal Adhesion
Cell Cortex
Cell Surface
Cell Junction
Cell-substrate Junction
Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
Lamellipodium Membrane
I Band
Molecular Function
Cytokine Activity
Protein Binding
Actin Binding
Integrin Binding
Protein Binding
Phosphatidylinositol-3,4,5-trisphosphate Binding
Protein Kinase Binding
Type I Transforming Growth Factor Beta Receptor Binding
SMAD Binding
Actin Filament Binding
Biological Process
Chemotaxis
Signal Transduction
Negative Regulation Of Myoblast Differentiation
Cell Adhesion
Cell-matrix Adhesion
Transforming Growth Factor Beta Receptor Signaling Pathway
Integrin-mediated Signaling Pathway
Regulation Of Cell Shape
Positive Regulation Of Epithelial To Mesenchymal Transition
Wnt Signaling Pathway
Regulation Of Cell Morphogenesis
Positive Regulation Of Cell Migration
Integrin Activation
Positive Regulation Of Integrin Activation
Cell Junction Assembly
Adherens Junction Maintenance
Substrate Adhesion-dependent Cell Spreading
Positive Regulation Of Myosin Light Chain Kinase Activity
Negative Regulation Of Vascular Permeability
Positive Regulation Of GTPase Activity
Negative Regulation Of Fat Cell Differentiation
Positive Regulation Of Osteoblast Differentiation
Focal Adhesion Assembly
Positive Regulation Of Stress Fiber Assembly
Positive Regulation Of Focal Adhesion Assembly
Positive Regulation Of Protein Kinase B Signaling
Limb Development
Negative Regulation Of Cell Death
Positive Regulation Of ERK1 And ERK2 Cascade
Protein Localization To Membrane
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Positive Regulation Of Protein Localization To Nucleus
Protein Localization To Cell Junction
Positive Regulation Of Mesenchymal Stem Cell Proliferation
Positive Regulation Of Wound Healing, Spreading Of Epidermal Cells
Pathways
Cell-extracellular matrix interactions
Drugs
Diseases
GWAS
Alzheimer's disease (late onset) (
24162737
)
Diastolic blood pressure (
27841878
)
Glaucoma (primary angle closure) (
27064256
)
Intraocular pressure (
29617998
29785010
31959993
30054594
)
Post bronchodilator FEV1/FVC ratio (
26634245
)
PR interval (
30046033
32439900
)
Prostate cancer (
23535732
)
Pulse pressure (
27841878
)
Systolic blood pressure (
28135244
27841878
)
Interacting Genes
131 interacting genes:
AACS
ABHD4
ACSF2
ACSM1
ALDH18A1
APOA1
APOA4
APOA5
AQP6
ARFIP1
ARFIP2
ARMC9
BIK
BNIP3
CAPNS2
CD160
CD40
CD79A
CLDN7
COQ8A
CPLX1
CPLX4
CREB3
CYP1A1
DDA1
DHRSX
ECPAS
ELOVL4
ERGIC3
FAM114A1
FARS2
FCGR2A
FCRL3
FERMT2
FFAR2
FNDC9
GAD1
GAD2
GJB1
GLTP
GOLGA2P10
GPX8
GTF3C1
HNRNPK
HSD17B13
JAGN1
JOSD2
KASH5
KCNJ6
KCNK5
KIR3DL3
LEUTX
LMNA
LMO2
LNX1
LRRC4C
LRRC59
MCEE
MCEMP1
MCFD2
MEOX2
MFF
MGST3
MIEF1
MRM1
MRRF
MTERF3
MTIF3
MYG1
NDRG4
NFU1
NTAQ1
PBX3
PCNA
PIMREG
PITPNC1
PLIN3
PNPO
POLL
PPIF
PPP2R3C
PSCA
PTPN9
RBFA
REEP2
RETREG3
RHBDD1
RMDN2
RNF185
RSRC2
RUSF1
SAR1A
SCARA5
SDCBP
SGCB
SH3GL1
SH3GLB1
SHMT2
SLC10A6
SLC18A2
SLC30A4
SLC35C2
SLC7A14
SNX1
SPATA8
SPG21
SSX3
SSX5
STING1
STOM
SUCLA2
SYNE4
SYT16
TBRG4
THAP4
TIMM44
TLCD4
TMED8
TMEM139
TMEM14B
TMEM35A
TMEM80
TMF1
TPD52L3
TSPAN31
TTPA
TUBB
TUFM
VARS2
ZNF391
ZNF599
8 interacting genes:
APP
CMTM5
FBLIM1
ILK
ITGB1
LIMS1
PARVA
TRIM15
Entrez ID
116173
10979
HPRD ID
06986
06374
Ensembl ID
ENSG00000166091
ENSG00000073712
Uniprot IDs
Q96DZ9
A0A024R687
Q96AC1
PDB IDs
2LGX
2LKO
2MSU
4F7H
6U4N
6XTJ
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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