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CMTM5 and APOA4
Data Source:
BioGRID
(two hybrid)
CMTM5
APOA4
Description
CKLF like MARVEL transmembrane domain containing 5
apolipoprotein A4
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Integral Component Of Membrane
Extracellular Region
Extracellular Space
Early Endosome
Endoplasmic Reticulum Lumen
Cytosol
Cell Surface
Very-low-density Lipoprotein Particle
High-density Lipoprotein Particle
Chylomicron
Collagen-containing Extracellular Matrix
Extracellular Exosome
Blood Microparticle
Molecular Function
Cytokine Activity
Protein Binding
Lipid Transporter Activity
Copper Ion Binding
Protein Binding
Phospholipid Binding
Lipid Binding
Cholesterol Binding
Antioxidant Activity
Phosphatidylcholine Binding
Identical Protein Binding
Protein Homodimerization Activity
Phosphatidylcholine-sterol O-acyltransferase Activator Activity
Cholesterol Transfer Activity
Biological Process
Chemotaxis
Signal Transduction
Negative Regulation Of Myoblast Differentiation
Retinoid Metabolic Process
Innate Immune Response In Mucosa
Cholesterol Biosynthetic Process
Lipid Transport
Response To Lipid Hydroperoxide
Leukocyte Cell-cell Adhesion
Cholesterol Metabolic Process
Positive Regulation Of Cholesterol Esterification
Positive Regulation Of Triglyceride Catabolic Process
Lipid Catabolic Process
Removal Of Superoxide Radicals
Regulation Of Intestinal Cholesterol Absorption
Regulation Of Cholesterol Transport
Cholesterol Efflux
Phospholipid Efflux
Chylomicron Remodeling
Very-low-density Lipoprotein Particle Remodeling
High-density Lipoprotein Particle Remodeling
Chylomicron Assembly
High-density Lipoprotein Particle Assembly
Negative Regulation Of Plasma Lipoprotein Oxidation
Response To Stilbenoid
Lipoprotein Metabolic Process
Cholesterol Homeostasis
Hydrogen Peroxide Catabolic Process
Reverse Cholesterol Transport
Cellular Protein Metabolic Process
Positive Regulation Of Fatty Acid Biosynthetic Process
Phosphatidylcholine Metabolic Process
Positive Regulation Of Lipid Biosynthetic Process
Positive Regulation Of Lipoprotein Lipase Activity
Lipid Homeostasis
Protein-lipid Complex Assembly
Triglyceride Homeostasis
Intermembrane Lipid Transfer
Pathways
Chylomicron assembly
Assembly of active LPL and LIPC lipase complexes
Chylomicron remodeling
Retinoid metabolism and transport
Retinoid metabolism and transport
Amyloid fiber formation
Drugs
Zinc
Copper
Zinc acetate
Diseases
GWAS
Apolipoprotein A-IV levels (
27412012
)
Body mass index (
31978080
)
Cholesterol, total (
19060911
20686565
)
Coronary artery disease (
29263402
)
Coronary heart disease (
21378990
)
Delirium (
29631748
)
Fasting triglyceride levels (
32603185
)
HDL cholesterol (
20864672
19060906
20686565
26582766
)
HDL cholesterol levels (
28334899
)
Hematological and biochemical traits (
20139978
)
Hypertriglyceridemia (
23505323
)
LDL cholesterol (
20864672
19060911
20686565
)
LDL cholesterol levels (
28334899
)
Lipid metabolism phenotypes (
22286219
)
Lipid traits (
24386095
)
Metabolic syndrome (
30382898
)
Metabolite levels (
22916037
)
Postprandial triglyceride levels (
32603185
)
Total cholesterol levels (
28334899
29403010
29615537
)
Triglyceride levels (
32203549
28334899
26763881
28371326
29615537
32335043
)
Triglycerides (
19074352
21909109
18193043
18193044
20864672
19060906
19060911
20139978
20686565
26582766
)
Interacting Genes
131 interacting genes:
AACS
ABHD4
ACSF2
ACSM1
ALDH18A1
APOA1
APOA4
APOA5
AQP6
ARFIP1
ARFIP2
ARMC9
BIK
BNIP3
CAPNS2
CD160
CD40
CD79A
CLDN7
COQ8A
CPLX1
CPLX4
CREB3
CYP1A1
DDA1
DHRSX
ECPAS
ELOVL4
ERGIC3
FAM114A1
FARS2
FCGR2A
FCRL3
FERMT2
FFAR2
FNDC9
GAD1
GAD2
GJB1
GLTP
GOLGA2P10
GPX8
GTF3C1
HNRNPK
HSD17B13
JAGN1
JOSD2
KASH5
KCNJ6
KCNK5
KIR3DL3
LEUTX
LMNA
LMO2
LNX1
LRRC4C
LRRC59
MCEE
MCEMP1
MCFD2
MEOX2
MFF
MGST3
MIEF1
MRM1
MRRF
MTERF3
MTIF3
MYG1
NDRG4
NFU1
NTAQ1
PBX3
PCNA
PIMREG
PITPNC1
PLIN3
PNPO
POLL
PPIF
PPP2R3C
PSCA
PTPN9
RBFA
REEP2
RETREG3
RHBDD1
RMDN2
RNF185
RSRC2
RUSF1
SAR1A
SCARA5
SDCBP
SGCB
SH3GL1
SH3GLB1
SHMT2
SLC10A6
SLC18A2
SLC30A4
SLC35C2
SLC7A14
SNX1
SPATA8
SPG21
SSX3
SSX5
STING1
STOM
SUCLA2
SYNE4
SYT16
TBRG4
THAP4
TIMM44
TLCD4
TMED8
TMEM139
TMEM14B
TMEM35A
TMEM80
TMF1
TPD52L3
TSPAN31
TTPA
TUBB
TUFM
VARS2
ZNF391
ZNF599
5 interacting genes:
AGTRAP
CMTM4
CMTM5
GPLD1
MAGEA6
Entrez ID
116173
337
HPRD ID
06986
00130
Ensembl ID
ENSG00000166091
ENSG00000110244
Uniprot IDs
Q96DZ9
P06727
PDB IDs
3S84
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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