CMTM5 and AACS

Data Source:
BioGRID (two hybrid)

		CMTM5	AACS
Description		CKLF like MARVEL transmembrane domain containing 5	acetoacetyl-CoA synthetase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Integral Component Of Membrane	Cytosol
	Molecular Function	Cytokine Activity Protein Binding	Protein Binding ATP Binding Acetoacetate-CoA Ligase Activity Butyrate-CoA Ligase Activity
	Biological Process	Chemotaxis Signal Transduction Negative Regulation Of Myoblast Differentiation	Liver Development Fatty Acid Metabolic Process Response To Nutrient Response To Purine-containing Compound Positive Regulation Of Insulin Secretion Response To Oleic Acid Response To Drug Response To Starvation Response To Ethanol Ketone Body Biosynthetic Process White Fat Cell Differentiation Adipose Tissue Development Cellular Response To Glucose Stimulus Cellular Response To Testosterone Stimulus Cellular Response To Cholesterol
Pathways			Synthesis of Ketone Bodies
Drugs
Diseases
GWAS			Parkinson's disease progression (cognitive) ( 33111402) Resistant hypertension ( 30237584) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		131 interacting genes: AACS ABHD4 ACSF2 ACSM1 ALDH18A1 APOA1 APOA4 APOA5 AQP6 ARFIP1 ARFIP2 ARMC9 BIK BNIP3 CAPNS2 CD160 CD40 CD79A CLDN7 COQ8A CPLX1 CPLX4 CREB3 CYP1A1 DDA1 DHRSX ECPAS ELOVL4 ERGIC3 FAM114A1 FARS2 FCGR2A FCRL3 FERMT2 FFAR2 FNDC9 GAD1 GAD2 GJB1 GLTP GOLGA2P10 GPX8 GTF3C1 HNRNPK HSD17B13 JAGN1 JOSD2 KASH5 KCNJ6 KCNK5 KIR3DL3 LEUTX LMNA LMO2 LNX1 LRRC4C LRRC59 MCEE MCEMP1 MCFD2 MEOX2 MFF MGST3 MIEF1 MRM1 MRRF MTERF3 MTIF3 MYG1 NDRG4 NFU1 NTAQ1 PBX3 PCNA PIMREG PITPNC1 PLIN3 PNPO POLL PPIF PPP2R3C PSCA PTPN9 RBFA REEP2 RETREG3 RHBDD1 RMDN2 RNF185 RSRC2 RUSF1 SAR1A SCARA5 SDCBP SGCB SH3GL1 SH3GLB1 SHMT2 SLC10A6 SLC18A2 SLC30A4 SLC35C2 SLC7A14 SNX1 SPATA8 SPG21 SSX3 SSX5 STING1 STOM SUCLA2 SYNE4 SYT16 TBRG4 THAP4 TIMM44 TLCD4 TMED8 TMEM139 TMEM14B TMEM35A TMEM80 TMF1 TPD52L3 TSPAN31 TTPA TUBB TUFM VARS2 ZNF391 ZNF599	1 interacting genes: CMTM5
Entrez ID		116173	65985
HPRD ID		06986	12391
Ensembl ID		ENSG00000166091	ENSG00000081760
Uniprot IDs		Q96DZ9	A0A024RBV2 Q86V21
PDB IDs
Enriched GO Terms of Interacting Partners?
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