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MAPK8IP2 and MAP2K3
Data Source:
HPRD
(in vivo)
MAPK8IP2
MAP2K3
Description
mitogen-activated protein kinase 8 interacting protein 2
mitogen-activated protein kinase kinase 3
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Postsynaptic Density
Protein-containing Complex
Neuronal Cell Body
Nucleoplasm
Cytosol
Membrane
Molecular Function
Amyloid-beta Binding
MAP-kinase Scaffold Activity
Structural Molecule Activity
Protein Binding
Kinesin Binding
Protein Kinase Binding
Protein-containing Complex Binding
Protein Serine/threonine Kinase Activity
MAP Kinase Kinase Activity
Protein Tyrosine Kinase Activity
Protein Binding
ATP Binding
Protein Kinase Binding
Biological Process
Behavioral Fear Response
Signal Complex Assembly
JNK Cascade
Mating Behavior
Regulation Of Signaling Receptor Activity
Positive Regulation Of Stress-activated MAPK Cascade
Social Behavior
Regulation Of JNK Cascade
Nonassociative Learning
Dendrite Morphogenesis
Regulation Of Synaptic Transmission, Glutamatergic
Excitatory Postsynaptic Potential
Regulation Of NMDA Receptor Activity
Regulation Of AMPA Receptor Activity
Negative Regulation Of Apoptotic Signaling Pathway
Activation Of MAPK Activity
Regulation Of Cytokine Production
Inflammatory Response
Signal Transduction
Peptidyl-tyrosine Phosphorylation
Negative Regulation Of Hippo Signaling
Cellular Response To Vascular Endothelial Growth Factor Stimulus
P38MAPK Cascade
Positive Regulation Of Blood Vessel Endothelial Cell Migration
Positive Regulation Of Protein Kinase Activity
Positive Regulation Of Transcription, DNA-templated
Cardiac Muscle Contraction
Pathways
Oxidative Stress Induced Senescence
activated TAK1 mediates p38 MAPK activation
Drugs
Fostamatinib
Diseases
GWAS
Gut microbiota relative abundance (Prevotella) (
33208821
)
Hip circumference (
28552196
)
Body mass index (
26426971
28892062
)
Interacting Genes
85 interacting genes:
ADRB2
AFG3L2
ANAPC10
APP
ASRGL1
BBS10
C1QTNF3
C22orf39
C8orf33
CFL1
CHN1
CRMP1
CRP
CTNNBL1
DUSP16
DUSP18
EGFR
ERBB2
ERG28
EZH2
FGF12
FGF13
FSCN1
GALNT3
GBP2
HLA-C
HOXC8
IGIP
ING4
ITSN1
KIFC2
KLC1
LEFTY2
LRP1
LRP2
LRP8
LSM8
MAGED4B
MAP2K3
MAP2K7
MAP3K10
MAP3K11
MAP3K12
MAPK10
MAPK8
MAPK8IP1
MAPK8IP3
MAPK9
MASP1
MNDA
MRE11
MSRB3
NDUFS6
NUMB
PLXNA3
POLR1H
PRSS23
RAI1
RBM4
RBX1
RPS6KB2
RYBP
SCLT1
SH2D1B
SLC39A13
SLPI
SMARCB1
SMS
SPINK2
SPSB3
SRP19
SYNE2
TARBP2
TIAM1
TMEM128
TP53BP2
UNC119
USP46
VCP
VPS33B
VRK2
YY1AP1
ZNF593
ZNF670
ZNF784
54 interacting genes:
AKT1
ALDOC
APP
ARAF
ARRB1
AURKA
BECN1
BRAF
CBLC
CCND2
CD44
CDC42
CDK4
CDK6
CDKN2B
CDKN2C
DCTN1
DYRK1B
ELK1
ERBB2
FZR1
GLIS2
HIF1A
KAT2A
KDELR2
LATS2
LRRK2
MAP2K5
MAP2K6
MAP3K2
MAP3K3
MAP3K4
MAPK12
MAPK14
MAPK3
MAPK8IP2
MET
NF1
NF2
NFIC
PLCB2
PTEN
RAF1
RASSF1
RPL13
SMAD1
SMAD7
STK11
TAOK1
TAOK2
TEAD2
TERT
TINF2
TP53
Entrez ID
23542
5606
HPRD ID
09674
03816
Ensembl ID
ENSG00000008735
ENSG00000034152
Uniprot IDs
Q13387
P46734
Q6FI23
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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