MAPK8IP2 and ING4

Data Source:
BioGRID (two hybrid)

		MAPK8IP2	ING4
Description		mitogen-activated protein kinase 8 interacting protein 2	inhibitor of growth family member 4
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Postsynaptic Density Protein-containing Complex Neuronal Cell Body	Histone Acetyltransferase Complex Nucleus Nucleoplasm Cytosol Intermediate Filament Cytoskeleton MOZ/MORF Histone Acetyltransferase Complex
	Molecular Function	Amyloid-beta Binding MAP-kinase Scaffold Activity Structural Molecule Activity Protein Binding Kinesin Binding Protein Kinase Binding Protein-containing Complex Binding	Transcription Coactivator Activity Protein Binding Methylated Histone Binding Metal Ion Binding
	Biological Process	Behavioral Fear Response Signal Complex Assembly JNK Cascade Mating Behavior Regulation Of Signaling Receptor Activity Positive Regulation Of Stress-activated MAPK Cascade Social Behavior Regulation Of JNK Cascade Nonassociative Learning Dendrite Morphogenesis Regulation Of Synaptic Transmission, Glutamatergic Excitatory Postsynaptic Potential Regulation Of NMDA Receptor Activity Regulation Of AMPA Receptor Activity Negative Regulation Of Apoptotic Signaling Pathway	DNA Replication Protein Acetylation Apoptotic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Cell Cycle Arrest Negative Regulation Of Cell Population Proliferation Positive Regulation Of Apoptotic Process Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Growth
Pathways			HATs acetylate histones
Drugs
Diseases
GWAS		Gut microbiota relative abundance (Prevotella) ( 33208821) Hip circumference ( 28552196)
Interacting Genes		85 interacting genes: ADRB2 AFG3L2 ANAPC10 APP ASRGL1 BBS10 C1QTNF3 C22orf39 C8orf33 CFL1 CHN1 CRMP1 CRP CTNNBL1 DUSP16 DUSP18 EGFR ERBB2 ERG28 EZH2 FGF12 FGF13 FSCN1 GALNT3 GBP2 HLA-C HOXC8 IGIP ING4 ITSN1 KIFC2 KLC1 LEFTY2 LRP1 LRP2 LRP8 LSM8 MAGED4B MAP2K3 MAP2K7 MAP3K10 MAP3K11 MAP3K12 MAPK10 MAPK8 MAPK8IP1 MAPK8IP3 MAPK9 MASP1 MNDA MRE11 MSRB3 NDUFS6 NUMB PLXNA3 POLR1H PRSS23 RAI1 RBM4 RBX1 RPS6KB2 RYBP SCLT1 SH2D1B SLC39A13 SLPI SMARCB1 SMS SPINK2 SPSB3 SRP19 SYNE2 TARBP2 TIAM1 TMEM128 TP53BP2 UNC119 USP46 VCP VPS33B VRK2 YY1AP1 ZNF593 ZNF670 ZNF784	21 interacting genes: BEX3 CDC34 EGLN1 EP300 GRIPAP1 H3-4 H3C1 HNRNPD HOXB9 JADE2 KAT7 MAPK8IP2 MSX1 MYC NAV2 RELA SUV39H1 TLX3 TP53 TRIM55 TRIM63
Entrez ID		23542	51147
HPRD ID		09674	09774
Ensembl ID		ENSG00000008735	ENSG00000111653
Uniprot IDs		Q13387	Q9UNL4
PDB IDs			2K1J 2M1R 2PNX 2VNF 4AFL
Enriched GO Terms of Interacting Partners?
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