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MAPK8IP2 and NDUFS6
Data Source:
BioGRID
(two hybrid)
MAPK8IP2
NDUFS6
Description
mitogen-activated protein kinase 8 interacting protein 2
NADH:ubiquinone oxidoreductase subunit S6
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Postsynaptic Density
Protein-containing Complex
Neuronal Cell Body
Mitochondrial Inner Membrane
Mitochondrial Respiratory Chain Complex I
Molecular Function
Amyloid-beta Binding
MAP-kinase Scaffold Activity
Structural Molecule Activity
Protein Binding
Kinesin Binding
Protein Kinase Binding
Protein-containing Complex Binding
NADH Dehydrogenase (ubiquinone) Activity
Electron Transfer Activity
Biological Process
Behavioral Fear Response
Signal Complex Assembly
JNK Cascade
Mating Behavior
Regulation Of Signaling Receptor Activity
Positive Regulation Of Stress-activated MAPK Cascade
Social Behavior
Regulation Of JNK Cascade
Nonassociative Learning
Dendrite Morphogenesis
Regulation Of Synaptic Transmission, Glutamatergic
Excitatory Postsynaptic Potential
Regulation Of NMDA Receptor Activity
Regulation Of AMPA Receptor Activity
Negative Regulation Of Apoptotic Signaling Pathway
Mitochondrial Electron Transport, NADH To Ubiquinone
Mitochondrial Respiratory Chain Complex I Assembly
Pathways
Respiratory electron transport
Complex I biogenesis
Drugs
NADH
Diseases
Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS
Gut microbiota relative abundance (Prevotella) (
33208821
)
Hip circumference (
28552196
)
Lack of perseverance (
30718321
)
Metabolite levels (
23823483
)
Interacting Genes
85 interacting genes:
ADRB2
AFG3L2
ANAPC10
APP
ASRGL1
BBS10
C1QTNF3
C22orf39
C8orf33
CFL1
CHN1
CRMP1
CRP
CTNNBL1
DUSP16
DUSP18
EGFR
ERBB2
ERG28
EZH2
FGF12
FGF13
FSCN1
GALNT3
GBP2
HLA-C
HOXC8
IGIP
ING4
ITSN1
KIFC2
KLC1
LEFTY2
LRP1
LRP2
LRP8
LSM8
MAGED4B
MAP2K3
MAP2K7
MAP3K10
MAP3K11
MAP3K12
MAPK10
MAPK8
MAPK8IP1
MAPK8IP3
MAPK9
MASP1
MNDA
MRE11
MSRB3
NDUFS6
NUMB
PLXNA3
POLR1H
PRSS23
RAI1
RBM4
RBX1
RPS6KB2
RYBP
SCLT1
SH2D1B
SLC39A13
SLPI
SMARCB1
SMS
SPINK2
SPSB3
SRP19
SYNE2
TARBP2
TIAM1
TMEM128
TP53BP2
UNC119
USP46
VCP
VPS33B
VRK2
YY1AP1
ZNF593
ZNF670
ZNF784
5 interacting genes:
FGFR3
KCNH2
MAP3K7
MAPK6
MAPK8IP2
Entrez ID
23542
4726
HPRD ID
09674
10356
Ensembl ID
ENSG00000008735
ENSG00000145494
Uniprot IDs
Q13387
O75380
Q6IBC4
PDB IDs
5XTB
5XTD
5XTH
5XTI
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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