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BICD2 and USP2
Data Source:
BioGRID
(two hybrid)
BICD2
USP2
Description
BICD cargo adaptor 2
ubiquitin specific peptidase 2
Image
GO Annotations
Cellular Component
Nuclear Envelope
Annulate Lamellae
Nuclear Pore
Cytoplasm
Golgi Apparatus
Centrosome
Cytosol
Plasma Membrane
Cytoplasmic Vesicle
Nucleoplasm
Cytoplasm
Centrosome
Membrane
Perinuclear Region Of Cytoplasm
Molecular Function
Protein Binding
Cytoskeletal Anchor Activity
Small GTPase Binding
Dynactin Binding
Dynein Light Intermediate Chain Binding
Dynein Complex Binding
Cysteine-type Endopeptidase Activity
Thiol-dependent Ubiquitin-specific Protease Activity
Protein Binding
Cyclin Binding
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Metal Ion Binding
Biological Process
Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum
Microtubule-based Movement
Protein Transport
Protein Localization To Organelle
Protein Localization To Golgi Apparatus
MRNA Transport
Centrosome Localization
Regulation Of Microtubule Cytoskeleton Organization
Minus-end-directed Organelle Transport Along Microtubule
Microtubule Anchoring At Microtubule Organizing Center
Negative Regulation Of Transcription By RNA Polymerase II
Ubiquitin-dependent Protein Catabolic Process
Cell Cycle
Muscle Organ Development
Protein Deubiquitination
Protein Phosphopantetheinylation
Circadian Regulation Of Gene Expression
Entrainment Of Circadian Clock By Photoperiod
Locomotor Rhythm
Positive Regulation Of Mitotic Cell Cycle
Circadian Behavior
Protein Stabilization
Pathways
COPI-independent Golgi-to-ER retrograde traffic
TNFR1-induced proapoptotic signaling
Regulation of TNFR1 signaling
TNFR1-induced NFkappaB signaling pathway
Ub-specific processing proteases
Regulation of TP53 Degradation
Drugs
Diseases
GWAS
Height (
31562340
)
Malaria (
31844061
)
Neutrophil count (
32888494
)
Platelet count (
32888494
)
Visceral adipose tissue/subcutaneous adipose tissue ratio (
22589738
)
White blood cell count (
32888494
)
Refractive error (
32231278
)
Serum uric acid levels (
30993211
)
Urate levels (
31985003
31578528
23263486
)
Interacting Genes
42 interacting genes:
ARHGAP45
CBR3
CCDC187
CCHCR1
DCTN1
DCTN2
DCX
FAM110A
FAM161A
FAM161B
FAM50B
GSK3B
HDAC4
LNX1
MFAP1
MOS
NEK9
PMF1
POLDIP3
PPP1R18
PRPF18
PRPF31
RAB6A
RAB6B
RBM41
SNW1
TBRG4
TCEA2
TCEANC
TSGA10IP
USP2
UTP14C
YES1
ZC2HC1C
ZMAT2
ZNF417
ZNF624
ZNF648
ZNF669
ZNF670
ZSCAN12
ZSCAN23
163 interacting genes:
ABI2
ACTN1
ACTN2
ACTN3
APP
ASPG
ATN1
AURKA
BAP1
BCAR1
BCL2L2-PABPN1
BEGAIN
BEND5
BHLHB9
BICD2
BIRC7
BRCA1
CADPS
CALCOCO2
CARD9
CBLC
CCDC136
CCDC57
CCDC85B
CCDC88B
CCND1
CEP63
CEP70
CRACR2A
CRACR2B
CRY1
CTNNB1
DDI1
DEPDC5
DISC1
DTX3
DUSP21
DYDC1
EFHC2
EIF4ENIF1
ENPP1
ERBB2
EXOC5
EXOSC8
GEMIN4
GOLGA2
GOLGA6A
GOLGA6L9
GRB7
GRIPAP1
H2AC20
HOMER3
HOOK1
HOOK2
IHO1
IKBKG
IKZF3
IL1RL2
INTS11
JAKMIP1
JRK
KAZN
KIFC3
KRT15
KRT27
KRT31
KRT33B
KRT34
KRT35
KRT40
LHX3
LHX4
LMNA
LMNB2
LNX2
LONRF1
LRSAM1
LZTS2
MALT1
MAP3K2
MDM2
MID2
MNAT1
MORN5
MRPL28
MTUS2
MYC
NAB2
NDEL1
NEFL
NFKB2
NOTCH1
OIP5
OPTN
ORC3
ORC5
PALB2
PCGF6
PCNA
PEX5
PIBF1
PICK1
PIK3R3
PLA2G2A
PLEKHG4
PNMA1
POU2AF1
PRDM14
PRR5L
RABEP1
RAD18
RBCK1
RFX6
RNF125
RNF126
RNF144B
RNF166
RUNDC3A
S100A10
SH2B2
SNCA
SORBS3
SPAG8
SPDYE4
STAT5B
TAX1BP1
TEKT4
TFIP11
TGFBR1
TLE5
TNFAIP2
TRAF1
TRAF2
TRAF6
TRAIP
TRIM21
TRIM23
TRIM27
TRIM34
TRIM35
TRIM39
TRIM46
TRIM5
TRIM50
TRIM54
TRIM63
TRIM74
TRIM8
TRIM9
TRIP6
UBE2S
UBOX5
USHBP1
USP15
USP21
USP54
VCAM1
VPS28
VPS52
ZAP70
ZBED1
ZIM2
ZRANB1
Entrez ID
23299
9099
HPRD ID
09826
05287
Ensembl ID
ENSG00000185963
ENSG00000036672
Uniprot IDs
Q8TD16
Q96FU2
O75604
PDB IDs
6OFP
6PSE
2HD5
2IBI
3NHE
3V6C
3V6E
5XU8
5XVE
6DGF
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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