BICD2 and ZSCAN23

Data Source:
BioGRID (two hybrid)

		BICD2	ZSCAN23
Description		BICD cargo adaptor 2	zinc finger and SCAN domain containing 23
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Annulate Lamellae Nuclear Pore Cytoplasm Golgi Apparatus Centrosome Cytosol Plasma Membrane Cytoplasmic Vesicle	Nucleus
	Molecular Function	Protein Binding Cytoskeletal Anchor Activity Small GTPase Binding Dynactin Binding Dynein Light Intermediate Chain Binding Dynein Complex Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Protein Transport Protein Localization To Organelle Protein Localization To Golgi Apparatus MRNA Transport Centrosome Localization Regulation Of Microtubule Cytoskeleton Organization Minus-end-directed Organelle Transport Along Microtubule Microtubule Anchoring At Microtubule Organizing Center	Regulation Of Transcription By RNA Polymerase II
Pathways		COPI-independent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Height ( 31562340) Malaria ( 31844061) Neutrophil count ( 32888494) Platelet count ( 32888494) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738) White blood cell count ( 32888494)	Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Brain morphology (MOSTest) ( 32665545) Composite immunoglobulin trait (IgA/IgM) ( 28628107) Fish- and plant-related diet ( 32066663) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Refractive error ( 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258) Schizophrenia ( 28991256) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		42 interacting genes: ARHGAP45 CBR3 CCDC187 CCHCR1 DCTN1 DCTN2 DCX FAM110A FAM161A FAM161B FAM50B GSK3B HDAC4 LNX1 MFAP1 MOS NEK9 PMF1 POLDIP3 PPP1R18 PRPF18 PRPF31 RAB6A RAB6B RBM41 SNW1 TBRG4 TCEA2 TCEANC TSGA10IP USP2 UTP14C YES1 ZC2HC1C ZMAT2 ZNF417 ZNF624 ZNF648 ZNF669 ZNF670 ZSCAN12 ZSCAN23	22 interacting genes: BICD2 CCDC130 CDR2L CEP70 DDIT4L GOLGA6L9 LHPP PCDHB12 PICK1 PPARA PRKAA2 SCAND1 SDCBP TRAF2 TULP3 ZKSCAN7 ZNF24 ZNF426 ZNF446 ZSCAN21 ZSCAN22 ZSCAN9
Entrez ID		23299	222696
HPRD ID		09826	19514
Ensembl ID		ENSG00000185963	ENSG00000187987
Uniprot IDs		Q8TD16 Q96FU2	Q3MJ62
PDB IDs		6OFP 6PSE
Enriched GO Terms of Interacting Partners?
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