BICD2 and ARHGAP45

Data Source:
BioGRID (two hybrid)

		BICD2	ARHGAP45
Description		BICD cargo adaptor 2	Rho GTPase activating protein 45
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GO Annotations	Cellular Component	Nuclear Envelope Annulate Lamellae Nuclear Pore Cytoplasm Golgi Apparatus Centrosome Cytosol Plasma Membrane Cytoplasmic Vesicle	Extracellular Region Cytosol Membrane Ruffle Membrane Secretory Granule Lumen Azurophil Granule Lumen
	Molecular Function	Protein Binding Cytoskeletal Anchor Activity Small GTPase Binding Dynactin Binding Dynein Light Intermediate Chain Binding Dynein Complex Binding	GTPase Activator Activity Protein Binding Metal Ion Binding
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Protein Transport Protein Localization To Organelle Protein Localization To Golgi Apparatus MRNA Transport Centrosome Localization Regulation Of Microtubule Cytoskeleton Organization Minus-end-directed Organelle Transport Along Microtubule Microtubule Anchoring At Microtubule Organizing Center	Intracellular Signal Transduction Neutrophil Degranulation Regulation Of Small GTPase Mediated Signal Transduction Activation Of GTPase Activity
Pathways		COPI-independent Golgi-to-ER retrograde traffic	Rho GTPase cycle Neutrophil degranulation
Drugs
Diseases
GWAS		Height ( 31562340) Malaria ( 31844061) Neutrophil count ( 32888494) Platelet count ( 32888494) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738) White blood cell count ( 32888494)
Interacting Genes		42 interacting genes: ARHGAP45 CBR3 CCDC187 CCHCR1 DCTN1 DCTN2 DCX FAM110A FAM161A FAM161B FAM50B GSK3B HDAC4 LNX1 MFAP1 MOS NEK9 PMF1 POLDIP3 PPP1R18 PRPF18 PRPF31 RAB6A RAB6B RBM41 SNW1 TBRG4 TCEA2 TCEANC TSGA10IP USP2 UTP14C YES1 ZC2HC1C ZMAT2 ZNF417 ZNF624 ZNF648 ZNF669 ZNF670 ZSCAN12 ZSCAN23	9 interacting genes: BICD2 GMIP GOLGA2 HSF2BP PIBF1 PPP1R13B RINT1 TRIM50 ZUP1
Entrez ID		23299	23526
HPRD ID		09826	03097
Ensembl ID		ENSG00000185963	ENSG00000180448
Uniprot IDs		Q8TD16 Q96FU2	B3KVA9 B3KXW7 F5H1R4 K7ES92 K7ES98 Q8IYN3 Q92619
PDB IDs		6OFP 6PSE	3D25 3FT3
Enriched GO Terms of Interacting Partners?
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