PPBP and PLEKHJ1

Data Source:
BioGRID (two hybrid)

		PPBP	PLEKHJ1
Description		pro-platelet basic protein	pleckstrin homology domain containing J1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Platelet Alpha Granule Lumen Tertiary Granule Lumen	Early Endosome Trans-Golgi Network Cytosol Recycling Endosome
	Molecular Function	Glucose Transmembrane Transporter Activity Protein Binding Chemokine Activity Growth Factor Activity CXCR Chemokine Receptor Binding	Protein Binding
	Biological Process	Platelet Degranulation Inflammatory Response G Protein-coupled Receptor Signaling Pathway Neutrophil Chemotaxis Defense Response To Bacterium Neutrophil Degranulation Positive Regulation Of Cell Division Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide Glucose Transmembrane Transport	Receptor Recycling Endosome Organization Retrograde Transport, Endosome To Golgi
Pathways		Platelet degranulation Chemokine receptors bind chemokines G alpha (i) signalling events Neutrophil degranulation
Drugs		Ethanesulfonic acid Copper
Diseases
GWAS		Metabolite levels ( 22916037)	Pulse pressure ( 26390057)
Interacting Genes		32 interacting genes: CCL13 CCL21 CCL26 CCL28 CCL5 CCL8 CELF1 CMTM6 COPG1 COPS7A COX17 CTSG CXCL10 CXCL11 CXCL12 CXCL14 CXCL6 CXCL9 CXCR1 CXCR2 DMWD EFNA1 MAPK6 MOB3B NDUFB11 NR4A1 PLEKHJ1 PMAIP1 RAB10 RPS27 SCFD1 STRN4	11 interacting genes: ACVR1 APP DNMT3B IKBKG LAGE3 NTAQ1 PHETA1 PHETA2 PIH1D2 PPBP TGFBR1
Entrez ID		5473	55111
HPRD ID		07171	15150
Ensembl ID		ENSG00000163736	ENSG00000104886
Uniprot IDs		P02775	K7EIZ3 Q9NW61
PDB IDs		1F9P 1NAP 1TVX
Enriched GO Terms of Interacting Partners?
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