PPBP and COX17

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PPBP	COX17
Description		pro-platelet basic protein	cytochrome c oxidase copper chaperone COX17
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Platelet Alpha Granule Lumen Tertiary Granule Lumen	Cytoplasm Mitochondrial Intermembrane Space
	Molecular Function	Glucose Transmembrane Transporter Activity Protein Binding Chemokine Activity Growth Factor Activity CXCR Chemokine Receptor Binding	Copper Ion Binding Protein Binding Copper Chaperone Activity Cuprous Ion Binding
	Biological Process	Platelet Degranulation Inflammatory Response G Protein-coupled Receptor Signaling Pathway Neutrophil Chemotaxis Defense Response To Bacterium Neutrophil Degranulation Positive Regulation Of Cell Division Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide Glucose Transmembrane Transport	Generation Of Precursor Metabolites And Energy Copper Ion Transport Positive Regulation Of Cell Population Proliferation Mitochondrial Cytochrome C Oxidase Assembly Positive Regulation Of Cytochrome-c Oxidase Activity
Pathways		Platelet degranulation Chemokine receptors bind chemokines G alpha (i) signalling events Neutrophil degranulation	Mitochondrial protein import
Drugs		Ethanesulfonic acid Copper
Diseases
GWAS		Metabolite levels ( 22916037)
Interacting Genes		32 interacting genes: CCL13 CCL21 CCL26 CCL28 CCL5 CCL8 CELF1 CMTM6 COPG1 COPS7A COX17 CTSG CXCL10 CXCL11 CXCL12 CXCL14 CXCL6 CXCL9 CXCR1 CXCR2 DMWD EFNA1 MAPK6 MOB3B NDUFB11 NR4A1 PLEKHJ1 PMAIP1 RAB10 RPS27 SCFD1 STRN4	11 interacting genes: COPS6 EEF1A1 ERG28 HADHB KATNAL1 KRTAP10-8 LRIF1 PPBP RBM48 TP53 UNC119
Entrez ID		5473	10063
HPRD ID		07171	05314
Ensembl ID		ENSG00000163736	ENSG00000138495
Uniprot IDs		P02775	Q14061
PDB IDs		1F9P 1NAP 1TVX	2L0Y 2LGQ 2RN9 2RNB
Enriched GO Terms of Interacting Partners?
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