PPBP and COPG1

Data Source:
BioGRID (two hybrid)

		PPBP	COPG1
Description		pro-platelet basic protein	COPI coat complex subunit gamma 1
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Platelet Alpha Granule Lumen Tertiary Granule Lumen	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol COPI Vesicle Coat Transport Vesicle
	Molecular Function	Glucose Transmembrane Transporter Activity Protein Binding Chemokine Activity Growth Factor Activity CXCR Chemokine Receptor Binding	Structural Molecule Activity Protein Binding
	Biological Process	Platelet Degranulation Inflammatory Response G Protein-coupled Receptor Signaling Pathway Neutrophil Chemotaxis Defense Response To Bacterium Neutrophil Degranulation Positive Regulation Of Cell Division Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide Glucose Transmembrane Transport	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Protein Secretion Establishment Of Golgi Localization Organelle Transport Along Microtubule
Pathways		Platelet degranulation Chemokine receptors bind chemokines G alpha (i) signalling events Neutrophil degranulation	COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs		Ethanesulfonic acid Copper	S-(Dimethylarsenic)Cysteine
Diseases
GWAS		Metabolite levels ( 22916037)	Height ( 31562340) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		32 interacting genes: CCL13 CCL21 CCL26 CCL28 CCL5 CCL8 CELF1 CMTM6 COPG1 COPS7A COX17 CTSG CXCL10 CXCL11 CXCL12 CXCL14 CXCL6 CXCL9 CXCR1 CXCR2 DMWD EFNA1 MAPK6 MOB3B NDUFB11 NR4A1 PLEKHJ1 PMAIP1 RAB10 RPS27 SCFD1 STRN4	19 interacting genes: ARCN1 ARF1 CDC42 COPB1 COPE COPG2 COPZ1 COPZ2 DRD1 H2AX PPBP PTGES3 RHOQ SACM1L SCYL1 SUMO2 TAPBP TMED10 WBP2
Entrez ID		5473	22820
HPRD ID		07171	09887
Ensembl ID		ENSG00000163736	ENSG00000181789
Uniprot IDs		P02775	Q9Y678
PDB IDs		1F9P 1NAP 1TVX	1R4X
Enriched GO Terms of Interacting Partners?
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