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EIF5 and PUM1
Data Source:
BioGRID
(two hybrid)
EIF5
PUM1
Description
eukaryotic translation initiation factor 5
pumilio RNA binding family member 1
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Plasma Membrane
P-body
Nucleoplasm
Cytoplasm
Cytosol
Cytoplasmic Stress Granule
Molecular Function
RNA Binding
Translation Initiation Factor Activity
GDP-dissociation Inhibitor Activity
Protein Binding
GTP Binding
Cadherin Binding
Eukaryotic Initiation Factor EIF2 Binding
RNA Binding
MRNA Binding
MRNA 3'-UTR Binding
Protein Binding
MiRNA Binding
Biological Process
Formation Of Translation Preinitiation Complex
Formation Of Cytoplasmic Translation Initiation Complex
Regulation Of Translational Initiation
Activation Of GTPase Activity
Spermatogenesis
Adult Locomotory Behavior
Posttranscriptional Regulation Of Gene Expression
Posttranscriptional Gene Silencing
Production Of MiRNAs Involved In Gene Silencing By MiRNA
Regulation Of MRNA Stability
Stem Cell Differentiation
Regulation Of Cell Cycle
Regulation Of Chromosome Segregation
Regulation Of Gene Silencing By MiRNA
MRNA Destabilization
Positive Regulation Of RIG-I Signaling Pathway
Positive Regulation Of Gene Silencing By MiRNA
Pathways
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit
Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS
Autism spectrum disorder or schizophrenia (
28540026
)
Body mass index (
26426971
)
Monocyte count (
29403010
)
Number of sexual partners (
30643258
)
Red blood cell traits (
23222517
)
Interacting Genes
16 interacting genes:
APP
CDC42
CSNK2A1
CSNK2B
DUSP12
EIF1AX
EIF1AY
EIF2S2
EIF3D
EIF3G
EIF4G1
EIF4G2
HSPB1
NCBP2
NRGN
PUM1
47 interacting genes:
ATXN1
EIF5
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR143
MIR145
MIR15B
MIR17
MIR18B
MIR199A1
MIR199A2
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR25
MIR29A
MIR29C
MIR34A
MIR7-1
MIR9-3
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
PRR12
SMAD1
Entrez ID
1983
9698
HPRD ID
03417
06230
Ensembl ID
ENSG00000100664
ENSG00000134644
Uniprot IDs
A0A024R6Q1
P55010
Q14671
PDB IDs
2E9H
2G2K
2IU1
1IB2
1M8W
1M8X
1M8Y
1M8Z
2YJY
3BSB
3BSX
3Q0L
3Q0M
3Q0N
3Q0O
3Q0P
5YKH
5YKI
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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