ARL4D and EIF2B1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ARL4D	EIF2B1
Description		ADP ribosylation factor like GTPase 4D	eukaryotic translation initiation factor 2B subunit alpha
Image		No pdb structure
GO Annotations	Cellular Component	Nucleolus Cytoplasm Plasma Membrane	Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 2B Complex Plasma Membrane Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding	Translation Initiation Factor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding Identical Protein Binding
	Biological Process	Intracellular Protein Transport Protein Secretion Vesicle-mediated Transport	Translational Initiation Regulation Of Translational Initiation Response To Heat Response To Glucose Oligodendrocyte Development Response To Peptide Hormone Regulation Of Catalytic Activity T Cell Receptor Signaling Pathway
Pathways			Recycling of eIF2:GDP
Drugs
Diseases			Leukoencephalopathy with vanishing white matter; Vanishing white matter disease; Childhood ataxia with diffuse central nervous system hypomyelination (CACH); Cree leukoencephalopathy (CLE)
GWAS			Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		22 interacting genes: APP ARL6IP1 CCDC102B CNPY4 CYTH2 DNAJA1 EIF2B1 EML4 EPRS1 MAPK8IP3 NDRG1 PGAM1 PRKCSH SMAD1 SMAD2 SMURF1 SNRPN TGFBR1 TLE1 TMEM230 UBR1 UNC119	21 interacting genes: ADRA2A ADRA2B ADRA2C ADRB2 ARL4D ATF5 BZW2 C1orf50 CREBBP EIF2B2 EIF2S1 EIF2S2 EPM2A GORASP2 MED29 MRPL4 NTAQ1 RD3 TRIM59 TRIML2 UBE2I
Entrez ID		379	1967
HPRD ID		02842	09458
Ensembl ID		ENSG00000175906	ENSG00000111361
Uniprot IDs		P49703	Q14232
PDB IDs			3ECS 6CAJ 6EZO 6K71 6K72 6O81 6O85 6O9Z
Enriched GO Terms of Interacting Partners?
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