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EHHADH and SCP2
Data Source:
HPRD
(in vitro)
EHHADH
SCP2
Description
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
sterol carrier protein 2
Image
No pdb structure
GO Annotations
Cellular Component
Peroxisome
Peroxisomal Matrix
Cytosol
Nucleoplasm
Mitochondrion
Peroxisome
Peroxisomal Matrix
Cytosol
Membrane
Protein-containing Complex
Intracellular Membrane-bounded Organelle
Molecular Function
3-hydroxyacyl-CoA Dehydrogenase Activity
Dodecenoyl-CoA Delta-isomerase Activity
Enoyl-CoA Hydratase Activity
Protein Binding
Long-chain-enoyl-CoA Hydratase Activity
Long-chain-3-hydroxyacyl-CoA Dehydrogenase Activity
Intramolecular Oxidoreductase Activity, Transposing C=C Bonds
Enzyme Binding
Fatty-acyl-CoA Binding
Acetyl-CoA C-acyltransferase Activity
Signaling Receptor Binding
Protein Binding
Cholesterol Binding
Sterol Binding
Propanoyl-CoA C-acyltransferase Activity
Long-chain Fatty Acyl-CoA Binding
Propionyl-CoA C2-trimethyltridecanoyltransferase Activity
Acetyl-CoA C-myristoyltransferase Activity
Oleic Acid Binding
Biological Process
Protein Targeting To Peroxisome
Fatty Acid Beta-oxidation
Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase
Protein Targeting To Peroxisome
Fatty Acid Beta-oxidation
Steroid Biosynthetic Process
Bile Acid Biosynthetic Process
Bile Acid Metabolic Process
Phospholipid Transport
Positive Regulation Of Intracellular Cholesterol Transport
Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase
Alpha-linolenic Acid Metabolic Process
Lipid Hydroperoxide Transport
Pathways
Beta-oxidation of very long chain fatty acids
Peroxisomal protein import
Peroxisomal protein import
alpha-linolenic acid (ALA) metabolism
Peroxisomal protein import
Peroxisomal protein import
TYSND1 cleaves peroxisomal proteins
Drugs
NADH
Diseases
Peroxisomal beta-oxidation enzyme deficiency, including: Acyl-CoA oxidase (ACOX) deficiency; D-bifunctional protein (DBP) deficiency; Perrault syndrome; Sterol carrier protein X (SCPx) deficiency; 2-Methylacyl-CoA racemase (AMCR) deficiency; Hypercholanemia
Leukoencephalopathy with dystonia and motor neuropathy
GWAS
Cognitive performance (
19734545
)
Major depressive disorder (
27519822
21042317
)
Interacting Genes
100 interacting genes:
AARS2
ACTB
ACTG1
ADARB1
ANKRD36B
ARMC12
ARMCX3
BHLHE40
BOLL
CAT
CBS
CCDC102B
CCDC13
CDR2L
CEP83
CISD2
CLDN18
CLDN5
CLK2
CMTM6
COQ9
CYB561
CYB561A3
DAAM2
DERL3
DES
EMP1
ERGIC1
FGF14
FUNDC1
GAS8
GMCL1
GRIPAP1
HID1
HIP1
HSD17B11
HTATIP2
JAGN1
KCTD6
KCTD9
KRTAP10-7
KRTAP4-11
LCN2
LEPROTL1
LYPD5
LZTFL1
LZTS2
MAB21L3
MID1
MTUS2
NACC1
NECAB2
OPRM1
ORMDL1
PAQR8
PICK1
PNMA1
PNMA5
PPP1R12C
PRKRA
PSTPIP1
PTGES
REL
RNF4
RPRM
RUSF1
SCARA5
SCP2
SDR16C5
SGCB
SLC14A2
SLC39A2
SMIM5
SMN1
SMN2
SSNA1
SSX2IP
SYNGR3
TMEM121
TMEM17
TMEM31
TMEM35A
TNIP1
TPP2
TRAF1
TRIM21
TRIM23
TRIM27
TRIM41
TRIM5
TRIM54
TRIM55
TRIM63
VAC14
ZBTB10
ZBTB26
ZBTB8A
ZBTB9
ZCCHC17
ZRANB1
9 interacting genes:
ACAA2
ACOX1
CACNA1A
CAV1
CREB3
EHHADH
PEX5
PITPNA
TRIP13
Entrez ID
1962
6342
HPRD ID
06125
01700
Ensembl ID
ENSG00000113790
ENSG00000116171
Uniprot IDs
Q08426
A0A384NY87
B2R761
E9PLD1
P22307
Q59HG9
PDB IDs
1QND
2C0L
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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