SCP2 and ACOX1

Data Source:
HPRD (in vitro)

		SCP2	ACOX1
Description		sterol carrier protein 2	acyl-CoA oxidase 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Peroxisome Peroxisomal Matrix Cytosol Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle	Peroxisome Peroxisomal Membrane Peroxisomal Matrix Cytosol Membrane
	Molecular Function	Fatty-acyl-CoA Binding Acetyl-CoA C-acyltransferase Activity Signaling Receptor Binding Protein Binding Cholesterol Binding Sterol Binding Propanoyl-CoA C-acyltransferase Activity Long-chain Fatty Acyl-CoA Binding Propionyl-CoA C2-trimethyltridecanoyltransferase Activity Acetyl-CoA C-myristoyltransferase Activity Oleic Acid Binding	Acyl-CoA Oxidase Activity Fatty Acid Binding Palmitoyl-CoA Oxidase Activity PDZ Domain Binding Protein Homodimerization Activity Protein N-terminus Binding Flavin Adenine Dinucleotide Binding FAD Binding
	Biological Process	Protein Targeting To Peroxisome Fatty Acid Beta-oxidation Steroid Biosynthetic Process Bile Acid Biosynthetic Process Bile Acid Metabolic Process Phospholipid Transport Positive Regulation Of Intracellular Cholesterol Transport Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Alpha-linolenic Acid Metabolic Process Lipid Hydroperoxide Transport	Very Long-chain Fatty Acid Metabolic Process Generation Of Precursor Metabolites And Energy Protein Targeting To Peroxisome Lipid Metabolic Process Prostaglandin Metabolic Process Spermatogenesis Fatty Acid Catabolic Process Regulation Of Lipid Metabolic Process Fatty Acid Oxidation Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Alpha-linolenic Acid Metabolic Process Hydrogen Peroxide Biosynthetic Process Lipid Homeostasis
Pathways		alpha-linolenic acid (ALA) metabolism Peroxisomal protein import Peroxisomal protein import TYSND1 cleaves peroxisomal proteins	Peroxisomal protein import Peroxisomal protein import TYSND1 cleaves peroxisomal proteins
Drugs			Flavin adenine dinucleotide (3R)-3-HYDROXYDODECANOIC ACID
Diseases		Peroxisomal beta-oxidation enzyme deficiency, including: Acyl-CoA oxidase (ACOX) deficiency; D-bifunctional protein (DBP) deficiency; Perrault syndrome; Sterol carrier protein X (SCPx) deficiency; 2-Methylacyl-CoA racemase (AMCR) deficiency; Hypercholanemia Leukoencephalopathy with dystonia and motor neuropathy	Peroxisomal beta-oxidation enzyme deficiency, including: Acyl-CoA oxidase (ACOX) deficiency; D-bifunctional protein (DBP) deficiency; Perrault syndrome; Sterol carrier protein X (SCPx) deficiency; 2-Methylacyl-CoA racemase (AMCR) deficiency; Hypercholanemia
GWAS			Body mass index ( 28552196) Diastolic blood pressure ( 27841878) Mean platelet volume ( 32888494) Pulse pressure ( 27841878) Systolic blood pressure ( 28135244 27841878) Urinary metabolite levels in chronic kidney disease ( 31959995) White matter hyperintensity burden ( 25663218)
Interacting Genes		9 interacting genes: ACAA2 ACOX1 CACNA1A CAV1 CREB3 EHHADH PEX5 PITPNA TRIP13	3 interacting genes: SCP2 SLC2A4 TYSND1
Entrez ID		6342	51
HPRD ID		01700	02030
Ensembl ID		ENSG00000116171	ENSG00000161533
Uniprot IDs		A0A384NY87 B2R761 E9PLD1 P22307 Q59HG9	Q15067
PDB IDs		1QND 2C0L
Enriched GO Terms of Interacting Partners?
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