EHHADH and SLC14A2

Data Source:
BioGRID (two hybrid)

		EHHADH	SLC14A2
Description		enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase	solute carrier family 14 member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Peroxisome Peroxisomal Matrix Cytosol	Plasma Membrane Membrane Integral Component Of Membrane Apical Plasma Membrane
	Molecular Function	3-hydroxyacyl-CoA Dehydrogenase Activity Dodecenoyl-CoA Delta-isomerase Activity Enoyl-CoA Hydratase Activity Protein Binding Long-chain-enoyl-CoA Hydratase Activity Long-chain-3-hydroxyacyl-CoA Dehydrogenase Activity Intramolecular Oxidoreductase Activity, Transposing C=C Bonds Enzyme Binding	Protein Binding Urea Transmembrane Transporter Activity Cell Adhesion Molecule Binding
	Biological Process	Protein Targeting To Peroxisome Fatty Acid Beta-oxidation Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase	Urea Transport Transmembrane Transport Urea Transmembrane Transport
Pathways		Beta-oxidation of very long chain fatty acids Peroxisomal protein import Peroxisomal protein import	Transport of bile salts and organic acids, metal ions and amine compounds
Drugs		NADH
Diseases
GWAS		Cognitive performance ( 19734545) Major depressive disorder ( 27519822 21042317)	Biochemical measures ( 19260141) Bladder cancer ( 24163127) Blood urea nitrogen levels ( 31152163 29403010) Cerebrospinal fluid clusterin levels ( 26545630) Cocaine dependence ( 31212010) FEV1 ( 30804560) Follicular lymphoma ( 25279986) Heel bone mineral density ( 30598549) Hematocrit ( 32888494) Hematological and biochemical traits ( 20139978) Hemoglobin ( 32888494) Intake of total sugars ( 31005972) Lateral orbital frontal cortex volume ( 31530798) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 30804560) Male-pattern baldness ( 27182965 28196072) Menarche (age at onset) ( 21102462) Metabolite levels ( 21909109 23823483) Nicotine withdrawal ( 29532581) Nicotine withdrawal symptom count ( 29532581) Pulse pressure ( 28135244 27841878) Red blood cell count ( 32888494) Refractive error ( 32231278) Renal function-related traits (BUN) ( 22797727) Smoking status (ever vs never smokers) ( 30643258) Spherical equivalent (joint analysis main effects and education interaction) ( 27020472) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Sum of carotid plaque area ( 32469969) Sum of stenosis ( 32469969) Systolic blood pressure ( 27841878) Urate levels ( 31578528)
Interacting Genes		100 interacting genes: AARS2 ACTB ACTG1 ADARB1 ANKRD36B ARMC12 ARMCX3 BHLHE40 BOLL CAT CBS CCDC102B CCDC13 CDR2L CEP83 CISD2 CLDN18 CLDN5 CLK2 CMTM6 COQ9 CYB561 CYB561A3 DAAM2 DERL3 DES EMP1 ERGIC1 FGF14 FUNDC1 GAS8 GMCL1 GRIPAP1 HID1 HIP1 HSD17B11 HTATIP2 JAGN1 KCTD6 KCTD9 KRTAP10-7 KRTAP4-11 LCN2 LEPROTL1 LYPD5 LZTFL1 LZTS2 MAB21L3 MID1 MTUS2 NACC1 NECAB2 OPRM1 ORMDL1 PAQR8 PICK1 PNMA1 PNMA5 PPP1R12C PRKRA PSTPIP1 PTGES REL RNF4 RPRM RUSF1 SCARA5 SCP2 SDR16C5 SGCB SLC14A2 SLC39A2 SMIM5 SMN1 SMN2 SSNA1 SSX2IP SYNGR3 TMEM121 TMEM17 TMEM31 TMEM35A TNIP1 TPP2 TRAF1 TRIM21 TRIM23 TRIM27 TRIM41 TRIM5 TRIM54 TRIM55 TRIM63 VAC14 ZBTB10 ZBTB26 ZBTB8A ZBTB9 ZCCHC17 ZRANB1	12 interacting genes: C4orf3 CMTM7 EHHADH LAT LRP10 PLN PLP2 SEC22A TMEM97 TNF TRARG1 VAMP5
Entrez ID		1962	8170
HPRD ID		06125	03366
Ensembl ID		ENSG00000113790	ENSG00000132874
Uniprot IDs		Q08426	Q15849
PDB IDs
Enriched GO Terms of Interacting Partners?
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