XIRP1 and NEB

Data Source:
BioGRID (two hybrid, pull down)

		XIRP1	NEB
Description		xin actin binding repeat containing 1	nebulin
Image		No pdb structure
GO Annotations	Cellular Component	Stress Fiber Focal Adhesion	Cytosol Actin Cytoskeleton Z Disc Extracellular Exosome
	Molecular Function	RNA Binding Protein Binding Actin Filament Binding	Protein Binding Structural Constituent Of Muscle Actin Filament Binding
	Biological Process	Actin Filament Organization Negative Regulation Of Protein Binding	Muscle Organ Development Somatic Muscle Development Muscle Filament Sliding Regulation Of Actin Filament Length Muscle Fiber Development Cardiac Muscle Thin Filament Assembly
Pathways			Striated Muscle Contraction
Drugs
Diseases			Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM) Nemaline myopathy
GWAS		Apolipoprotein A1 levels ( 32203549) Cognitive decline rate in late mild cognitive impairment ( 26252872) Daytime sleep phenotypes ( 27126917) Social communication problems ( 24564958)	Asparaginase-induced acute pancreatitis in acute lymphoblastic leukemia (onset time) ( 27114598) Creatine kinase levels ( 29403010) Estimated glomerular filtration rate ( 31152163 31451708) Letter-number span reordering ( 31596458) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Rapid automised naming of letters ( 30741946) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		8 interacting genes: ACTA1 ENAH EVL FLNC NEB NEBL SH3RF1 VASP	24 interacting genes: ABI1 ACO1 ACTG2 ACTN4 AKTIP APC CALM1 DES ENO3 LIMS1 MTDH MYOM2 MYPN PTPN11 STRADB TMOD1 TMOD4 TPM1 TPM2 TRIM55 TRIM63 TTN XIRP1 XIRP2
Entrez ID		165904	4703
HPRD ID		16727	01196
Ensembl ID		ENSG00000168334	ENSG00000183091
Uniprot IDs		Q702N8	P20929 Q05C45 Q96MF8
PDB IDs			1ARK 1NEB
Enriched GO Terms of Interacting Partners?
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