XIRP1 and EVL

Data Source:
BioGRID (two hybrid)

		XIRP1	EVL
Description		xin actin binding repeat containing 1	Enah/Vasp-like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Stress Fiber Focal Adhesion	Cytoplasm Cytosol Cytoskeleton Focal Adhesion Membrane Lamellipodium
	Molecular Function	RNA Binding Protein Binding Actin Filament Binding	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding
	Biological Process	Actin Filament Organization Negative Regulation Of Protein Binding	Actin Filament Organization Cell Surface Receptor Signaling Pathway Nervous System Development Axon Guidance Actin Polymerization Or Depolymerization Animal Organ Morphogenesis Negative Regulation Of Epithelial Cell Migration Positive Regulation Of Actin Filament Polymerization Actin Nucleation Protein Homotetramerization Positive Regulation Of Stress Fiber Assembly Negative Regulation Of Ruffle Assembly
Pathways			Generation of second messenger molecules Signaling by ROBO receptors Signaling by ROBO receptors RHO GTPases Activate Formins
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Cognitive decline rate in late mild cognitive impairment ( 26252872) Daytime sleep phenotypes ( 27126917) Social communication problems ( 24564958)	Blood protein levels ( 30072576) White matter hyperintensities ( 32358547) White matter hyperintensity burden ( 25663218)
Interacting Genes		8 interacting genes: ACTA1 ENAH EVL FLNC NEB NEBL SH3RF1 VASP	33 interacting genes: ABI1 ABI3 ABL1 APBB1 APBB1IP CRKL DNMBP ENAH FYB1 FYN HCK HTT LYN PFN2 POT1 PRPF40A RAD51 SEMA6A SH3RF1 SPTA1 SPTAN1 SRC TCERG1 TERF1 TES TRIM9 VASP WAS WASL XIRP1 ZDHHC17 ZNF655 ZYX
Entrez ID		165904	51466
HPRD ID		16727	10942
Ensembl ID		ENSG00000168334	ENSG00000196405
Uniprot IDs		Q702N8	A0A024R6K5 Q9UI08
PDB IDs
Enriched GO Terms of Interacting Partners?
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