NEB and STRADB

Data Source:
BioGRID (two hybrid)

		NEB	STRADB
Description		nebulin	STE20 related adaptor beta
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Actin Cytoskeleton Z Disc Extracellular Exosome	Nucleus Cytoplasm Cytosol Aggresome
	Molecular Function	Protein Binding Structural Constituent Of Muscle Actin Filament Binding	Protein Kinase Activity Protein Binding ATP Binding
	Biological Process	Muscle Organ Development Somatic Muscle Development Muscle Filament Sliding Regulation Of Actin Filament Length Muscle Fiber Development Cardiac Muscle Thin Filament Assembly	Cell Morphogenesis Protein Phosphorylation Protein Export From Nucleus Cell Cycle Arrest JNK Cascade Activation Of Protein Kinase Activity Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways		Striated Muscle Contraction	Energy dependent regulation of mTOR by LKB1-AMPK
Drugs
Diseases		Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM) Nemaline myopathy
GWAS		Asparaginase-induced acute pancreatitis in acute lymphoblastic leukemia (onset time) ( 27114598) Creatine kinase levels ( 29403010) Estimated glomerular filtration rate ( 31152163 31451708) Letter-number span reordering ( 31596458) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Rapid automised naming of letters ( 30741946) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		24 interacting genes: ABI1 ACO1 ACTG2 ACTN4 AKTIP APC CALM1 DES ENO3 LIMS1 MTDH MYOM2 MYPN PTPN11 STRADB TMOD1 TMOD4 TPM1 TPM2 TRIM55 TRIM63 TTN XIRP1 XIRP2	7 interacting genes: CAB39 GRB2 MAP3K7 NEB STK11 TRAF6 XIAP
Entrez ID		4703	55437
HPRD ID		01196	09546
Ensembl ID		ENSG00000183091	ENSG00000082146
Uniprot IDs		P20929 Q05C45 Q96MF8	Q9C0K7
PDB IDs		1ARK 1NEB
Enriched GO Terms of Interacting Partners?
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