XIRP1 and ENAH

Data Source:
BioGRID (two hybrid)

		XIRP1	ENAH
Description		xin actin binding repeat containing 1	ENAH actin regulator
Image		No pdb structure
GO Annotations	Cellular Component	Stress Fiber Focal Adhesion	Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Lamellipodium Cell Junction Filopodium Synapse
	Molecular Function	RNA Binding Protein Binding Actin Filament Binding	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding WW Domain Binding
	Biological Process	Actin Filament Organization Negative Regulation Of Protein Binding	Axon Guidance Actin Polymerization Or Depolymerization Actin Polymerization-dependent Cell Motility
Pathways			Generation of second messenger molecules Signaling by ROBO receptors Signaling by ROBO receptors
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Cognitive decline rate in late mild cognitive impairment ( 26252872) Daytime sleep phenotypes ( 27126917) Social communication problems ( 24564958)	Delirium ( 29631748) Depression in smokers ( 30219690) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Neuroticism ( 27067015) Obesity-related traits ( 23251661)
Interacting Genes		8 interacting genes: ACTA1 ENAH EVL FLNC NEB NEBL SH3RF1 VASP	27 interacting genes: ABI1 ABI2 ABI3 ABL1 APBB1 BAIAP2 DNMBP EVL FAT1 FYB1 GPHN HMGB1 KLHDC3 MAPK1 PFN1 PRPF40A RAC1 RAD51 ROBO4 SPTA1 TERF2IP TES VASP WAS XIRP1 YAP1 ZYX
Entrez ID		165904	55740
HPRD ID		16727	12360
Ensembl ID		ENSG00000168334	ENSG00000154380
Uniprot IDs		Q702N8	A0A4D6J698 Q8N8S7
PDB IDs			2HO2 2IYB 2XQN 4MY6 5N91 5N9C 5N9P 5NAJ 5NBF 5NBX 5NC2 5NC7 5NCF 5NCG 5NCP 5ND0 5NDU 5NEG 6RCF 6RCJ 6RD2 6XVT 6XXR 7A5M
Enriched GO Terms of Interacting Partners?
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