NEB and ACTG2

Data Source:
BioGRID (pull down)

		NEB	ACTG2
Description		nebulin	actin gamma 2, smooth muscle
Image
GO Annotations	Cellular Component	Cytosol Actin Cytoskeleton Z Disc Extracellular Exosome	Extracellular Space Cytoplasm Cytosol Dynactin Complex Lamellipodium Filopodium Myosin Filament Cell Body Extracellular Exosome Cell Periphery Blood Microparticle
	Molecular Function	Protein Binding Structural Constituent Of Muscle Actin Filament Binding	ATP Binding
	Biological Process	Muscle Organ Development Somatic Muscle Development Muscle Filament Sliding Regulation Of Actin Filament Length Muscle Fiber Development Cardiac Muscle Thin Filament Assembly	Muscle Contraction Positive Regulation Of Gene Expression Mesenchyme Migration
Pathways		Striated Muscle Contraction	Smooth Muscle Contraction
Drugs
Diseases		Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM) Nemaline myopathy
GWAS		Asparaginase-induced acute pancreatitis in acute lymphoblastic leukemia (onset time) ( 27114598) Creatine kinase levels ( 29403010) Estimated glomerular filtration rate ( 31152163 31451708) Letter-number span reordering ( 31596458) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Rapid automised naming of letters ( 30741946) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097) Squamous cell lung carcinoma ( 28604730)	Parent of origin effect on receptive language ability (paternal) ( 32635940)
Interacting Genes		24 interacting genes: ABI1 ACO1 ACTG2 ACTN4 AKTIP APC CALM1 DES ENO3 LIMS1 MTDH MYOM2 MYPN PTPN11 STRADB TMOD1 TMOD4 TPM1 TPM2 TRIM55 TRIM63 TTN XIRP1 XIRP2	4 interacting genes: EMD MLH1 NEB SHBG
Entrez ID		4703	72
HPRD ID		01196	00016
Ensembl ID		ENSG00000183091	ENSG00000163017
Uniprot IDs		P20929 Q05C45 Q96MF8	P63267
PDB IDs		1ARK 1NEB	6JAT
Enriched GO Terms of Interacting Partners?
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