TEKT5 and BAG4

Data Source:
BioGRID (two hybrid)

		TEKT5	BAG4
Description		tektin 5	BAG cochaperone 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Microtubule Cytoskeleton Sperm Flagellum	Nucleus Cytoplasm Cytosol Plasma Membrane Membrane
	Molecular Function	Protein Binding	Adenyl-nucleotide Exchange Factor Activity RNA Binding Protein Binding Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Protein-containing Complex Binding Chaperone Binding
	Biological Process	Cilium Assembly Cilium Movement Involved In Cell Motility	Protein Folding Positive Regulation Of Fibroblast Migration Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Peptidyl-serine Phosphorylation Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of Apoptotic Process Positive Regulation Of Cell Adhesion Protein Stabilization Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Protein Kinase B Signaling Cellular Response To Tumor Necrosis Factor Cellular Response To Epidermal Growth Factor Stimulus Protein Localization To Plasma Membrane Negative Regulation Of MRNA Modification Ruffle Assembly Regulation Of Cellular Response To Heat Negative Regulation Of Protein Targeting To Mitochondrion Negative Regulation Of Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity
Pathways			Regulation of HSF1-mediated heat shock response Signaling by FGFR1 in disease TNF signaling Signaling by plasma membrane FGFR1 fusions
Drugs
Diseases
GWAS		Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Chronic obstructive pulmonary disease ( 30804561) Eating disorders ( 23568457) Lung adenocarcinoma ( 28604730) Lung function (FEV1/FVC) ( 26635082 30804560) Neonatal total 25-hydroxyvitamin D levels (maternal genetic effect) ( 32047095) Nickel levels ( 26025379) Normal facial asymmetry (angle of surface orientation score) ( 30631343) Peak expiratory flow ( 30804560) Resting heart rate ( 27798624)	Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 28991256 29483656)
Interacting Genes		46 interacting genes: AKAP8L BAG4 C19orf54 C7orf31 CABP2 CSKMT DTX2 EPHB6 EYA2 FNDC3B FOXH1 FOXI1 HGS HOXA1 HOXB6 KLHL38 KRTAP12-4 KRTAP15-1 KRTAP19-6 KRTAP19-7 KRTAP6-2 LASP1 MAPKBP1 MGAT5B NFKBID NHLRC2 PITX1 PLSCR4 PROP1 PSMB4 QRICH1 RBPMS RORB RUNX1 SMARCB1 SMUG1 SPAG8 SSC4D TBX15 TLX3 TNS2 TOX2 USP54 VENTX ZMYND12 ZNF76	117 interacting genes: ABI2 ACOT7 ADAMTSL4 ALG13 APOBEC1 ARID5A ATAD2 ATP23 BAP1 BCAS3 BCL2 BCL6B BEX1 BLZF1 C3orf38 CASP2 CASZ1 CBFA2T2 CCL5 DDIT4L DIRAS3 DZIP3 EFEMP1 EPSTI1 ERRFI1 FAM214B FAM222B FARS2 FTH1 FYN GLCE GPANK1 GPS2 GRAP2 HOXA1 HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA8 IL13RA2 IL24 IST1 ITIH5 KCTD6 KCTD7 KIF5B KLK5 KLK7 KLK9 KRTAP13-1 KRTAP13-4 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP6-3 LASP1 LRATD2 LYPD3 MAGED1 MEI4 MRC2 MTA3 MYOZ1 MYOZ3 MYPOP NAT2 ODF1 ODF3L1 P4HA3 PDCD6 PDLIM2 PEF1 PGRMC2 PHF19 PLAC8 PPIL6 PPP1R32 PRDM14 PSMB5 PYCR3 RAMAC RASL10B RHOBTB2 RNF20 RPL22 RUNX1 SAMD4A SAXO1 SCGB3A1 SH3RF2 SIAH1 SNRPB SNRPC SS18L1 SUOX TBC1D3B TBC1D3G TBC1D7 TCL1B TEKT5 TFAP2D THRSP TINAGL1 TLE5 TNFRSF1A TNFRSF25 TRAPPC6A TSG101 UNKL USP22 VPS37C ZBTB45 ZBTB5 ZIM2
Entrez ID		146279	9530
HPRD ID		08736	04861
Ensembl ID		ENSG00000153060	ENSG00000156735
Uniprot IDs		Q96M29	O95429
PDB IDs			1M62 1M7K
Enriched GO Terms of Interacting Partners?
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