TEKT5 and TBX15

Data Source:
BioGRID (two hybrid)

		TEKT5	TBX15
Description		tektin 5	T-box transcription factor 15
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Microtubule Cytoskeleton Sperm Flagellum	Chromatin RNA Polymerase II Transcription Repressor Complex
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Protein Homodimerization Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Cilium Assembly Cilium Movement Involved In Cell Motility	Negative Regulation Of Transcription By RNA Polymerase II Cell Fate Specification Regulation Of Transcription By RNA Polymerase II Embryonic Cranial Skeleton Morphogenesis
Pathways
Drugs
Diseases			Cousin syndrome
GWAS		Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Chronic obstructive pulmonary disease ( 30804561) Eating disorders ( 23568457) Lung adenocarcinoma ( 28604730) Lung function (FEV1/FVC) ( 26635082 30804560) Neonatal total 25-hydroxyvitamin D levels (maternal genetic effect) ( 32047095) Nickel levels ( 26025379) Normal facial asymmetry (angle of surface orientation score) ( 30631343) Peak expiratory flow ( 30804560) Resting heart rate ( 27798624)	Adult body size ( 32376654) Antitragus size ( 26105758) Birth weight ( 31043758) Body mass index ( 28892062 25673413) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Breast size ( 27182965) Chin dimples ( 27182965) Congenital heart malformation ( 23708190) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Ear morphology ( 26105758) Excessive hairiness ( 29895819) Facial morphology ( 31763980) Facial morphology traits (63 three-dimensional facial segments) ( 29459680) Folding of antihelix ( 26105758) Heel bone mineral density ( 30598549 28869591) Height ( 31562340) Lung function (FVC) ( 28166213) Lung function (low FEV1 vs high FEV1) ( 26423011) Male-pattern baldness ( 27182965 28196072) Physiological traits ( 31902109) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 25673412 28448500) Waist-hip ratio ( 25673412 20935629) Waist-to-hip ratio adjusted for BMI ( 28552196) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI in inactive individuals ( 28448500) Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625) Waist-to-hip ratio adjusted for body mass index ( 26785701 25673412 28448500)
Interacting Genes		46 interacting genes: AKAP8L BAG4 C19orf54 C7orf31 CABP2 CSKMT DTX2 EPHB6 EYA2 FNDC3B FOXH1 FOXI1 HGS HOXA1 HOXB6 KLHL38 KRTAP12-4 KRTAP15-1 KRTAP19-6 KRTAP19-7 KRTAP6-2 LASP1 MAPKBP1 MGAT5B NFKBID NHLRC2 PITX1 PLSCR4 PROP1 PSMB4 QRICH1 RBPMS RORB RUNX1 SMARCB1 SMUG1 SPAG8 SSC4D TBX15 TLX3 TNS2 TOX2 USP54 VENTX ZMYND12 ZNF76	12 interacting genes: ATXN1 DOK6 DTX2 HOXA1 MYOZ3 NTAQ1 POLE2 RHOBTB3 TBX6 TEKT5 VENTX VGLL3
Entrez ID		146279	6913
HPRD ID		08736	16035
Ensembl ID		ENSG00000153060	ENSG00000092607
Uniprot IDs		Q96M29	Q8N8P2 Q96SF7
PDB IDs
Enriched GO Terms of Interacting Partners?
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