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BAG4 and BAP1
Data Source:
BioGRID
(two hybrid)
BAG4
BAP1
Description
BAG cochaperone 4
BRCA1 associated protein 1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Plasma Membrane
Membrane
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
PR-DUB Complex
Molecular Function
Adenyl-nucleotide Exchange Factor Activity
RNA Binding
Protein Binding
Heat Shock Protein Binding
Ubiquitin Protein Ligase Binding
Protein-containing Complex Binding
Chaperone Binding
Chromatin Binding
Thiol-dependent Ubiquitin-specific Protease Activity
Protein Binding
Peptidase Activity
Cysteine-type Peptidase Activity
Biological Process
Protein Folding
Positive Regulation Of Fibroblast Migration
Positive Regulation Of Actin Filament Polymerization
Positive Regulation Of Peptidyl-serine Phosphorylation
Tumor Necrosis Factor-mediated Signaling Pathway
Negative Regulation Of Apoptotic Process
Positive Regulation Of Cell Adhesion
Protein Stabilization
Positive Regulation Of Stress Fiber Assembly
Positive Regulation Of Protein Kinase B Signaling
Cellular Response To Tumor Necrosis Factor
Cellular Response To Epidermal Growth Factor Stimulus
Protein Localization To Plasma Membrane
Negative Regulation Of MRNA Modification
Ruffle Assembly
Regulation Of Cellular Response To Heat
Negative Regulation Of Protein Targeting To Mitochondrion
Negative Regulation Of Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity
Regulation Of Cell Growth
Cellular Protein Modification Process
Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Cell Population Proliferation
Response To Inorganic Substance
Protein Deubiquitination
Protein Phosphopantetheinylation
Monoubiquitinated Protein Deubiquitination
Monoubiquitinated Histone H2A Deubiquitination
Negative Regulation Of Transcription, DNA-templated
Regulation Of Inflammatory Response
Regulation Of Cell Cycle
Macrophage Homeostasis
Protein K48-linked Deubiquitination
Regulation Of Cytokine Production Involved In Inflammatory Response
Positive Regulation Of Protein Targeting To Mitochondrion
Pathways
Regulation of HSF1-mediated heat shock response
Signaling by FGFR1 in disease
TNF signaling
Signaling by plasma membrane FGFR1 fusions
UCH proteinases
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Drugs
Diseases
GWAS
Autism spectrum disorder or schizophrenia (
28540026
)
Schizophrenia (
28991256
29483656
)
Autism spectrum disorder or schizophrenia (
28540026
)
Bipolar disorder (
21926972
)
Parkinson's disease (
28892059
)
Schizophrenia (
23974872
)
Interacting Genes
117 interacting genes:
ABI2
ACOT7
ADAMTSL4
ALG13
APOBEC1
ARID5A
ATAD2
ATP23
BAP1
BCAS3
BCL2
BCL6B
BEX1
BLZF1
C3orf38
CASP2
CASZ1
CBFA2T2
CCL5
DDIT4L
DIRAS3
DZIP3
EFEMP1
EPSTI1
ERRFI1
FAM214B
FAM222B
FARS2
FTH1
FYN
GLCE
GPANK1
GPS2
GRAP2
HOXA1
HSPA1A
HSPA1B
HSPA1L
HSPA2
HSPA6
HSPA8
IL13RA2
IL24
IST1
ITIH5
KCTD6
KCTD7
KIF5B
KLK5
KLK7
KLK9
KRTAP13-1
KRTAP13-4
KRTAP4-12
KRTAP4-2
KRTAP4-4
KRTAP4-5
KRTAP6-3
LASP1
LRATD2
LYPD3
MAGED1
MEI4
MRC2
MTA3
MYOZ1
MYOZ3
MYPOP
NAT2
ODF1
ODF3L1
P4HA3
PDCD6
PDLIM2
PEF1
PGRMC2
PHF19
PLAC8
PPIL6
PPP1R32
PRDM14
PSMB5
PYCR3
RAMAC
RASL10B
RHOBTB2
RNF20
RPL22
RUNX1
SAMD4A
SAXO1
SCGB3A1
SH3RF2
SIAH1
SNRPB
SNRPC
SS18L1
SUOX
TBC1D3B
TBC1D3G
TBC1D7
TCL1B
TEKT5
TFAP2D
THRSP
TINAGL1
TLE5
TNFRSF1A
TNFRSF25
TRAPPC6A
TSG101
UNKL
USP22
VPS37C
ZBTB45
ZBTB5
ZIM2
27 interacting genes:
BAG4
BCAR3
BRCA1
CASP8
CBLC
CBX5
ESR1
H2AC18
H2AC20
H2AC4
IGF1R
ITPR3
KLF5
LINC00598
MAP3K1
NBN
PTPRJ
RB1CC1
TRIM63
UBC
UBE2O
USP15
USP2
USP21
USP28
XRCC3
YY1
Entrez ID
9530
8314
HPRD ID
04861
04366
Ensembl ID
ENSG00000156735
ENSG00000163930
Uniprot IDs
O95429
A0A024R305
F8W6N3
Q92560
PDB IDs
1M62
1M7K
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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