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BAG4 and HOXA1
Data Source:
BioGRID
(two hybrid)
BAG4
HOXA1
Description
BAG cochaperone 4
homeobox A1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Plasma Membrane
Membrane
Chromatin
Nucleus
Molecular Function
Adenyl-nucleotide Exchange Factor Activity
RNA Binding
Protein Binding
Heat Shock Protein Binding
Ubiquitin Protein Ligase Binding
Protein-containing Complex Binding
Chaperone Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Protein Binding
Identical Protein Binding
Sequence-specific DNA Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Protein Folding
Positive Regulation Of Fibroblast Migration
Positive Regulation Of Actin Filament Polymerization
Positive Regulation Of Peptidyl-serine Phosphorylation
Tumor Necrosis Factor-mediated Signaling Pathway
Negative Regulation Of Apoptotic Process
Positive Regulation Of Cell Adhesion
Protein Stabilization
Positive Regulation Of Stress Fiber Assembly
Positive Regulation Of Protein Kinase B Signaling
Cellular Response To Tumor Necrosis Factor
Cellular Response To Epidermal Growth Factor Stimulus
Protein Localization To Plasma Membrane
Negative Regulation Of MRNA Modification
Ruffle Assembly
Regulation Of Cellular Response To Heat
Negative Regulation Of Protein Targeting To Mitochondrion
Negative Regulation Of Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity
Regulation Of Transcription By RNA Polymerase II
Multicellular Organism Development
Sensory Perception Of Sound
Optokinetic Behavior
Anatomical Structure Morphogenesis
Abducens Nerve Formation
Outer Ear Morphogenesis
Positive Regulation Of Transcription By RNA Polymerase II
Embryonic Neurocranium Morphogenesis
Inner Ear Development
Artery Morphogenesis
Regulation Of Behavior
Cognition
Neuromuscular Process
Artery Development
Semicircular Canal Formation
Cochlea Development
Cochlea Morphogenesis
Pathways
Regulation of HSF1-mediated heat shock response
Signaling by FGFR1 in disease
TNF signaling
Signaling by plasma membrane FGFR1 fusions
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
Bosley-Salih-Alorainy syndrome and Athabascan brainstem dysgenesis syndrome
GWAS
Autism spectrum disorder or schizophrenia (
28540026
)
Schizophrenia (
28991256
29483656
)
Chronic venous disease (
28374850
)
Macular thickness (
30535121
)
Multiple sclerosis (
31604244
)
Small cell lung carcinoma (
28604730
)
Tonsillectomy (
27182965
28928442
)
Interacting Genes
117 interacting genes:
ABI2
ACOT7
ADAMTSL4
ALG13
APOBEC1
ARID5A
ATAD2
ATP23
BAP1
BCAS3
BCL2
BCL6B
BEX1
BLZF1
C3orf38
CASP2
CASZ1
CBFA2T2
CCL5
DDIT4L
DIRAS3
DZIP3
EFEMP1
EPSTI1
ERRFI1
FAM214B
FAM222B
FARS2
FTH1
FYN
GLCE
GPANK1
GPS2
GRAP2
HOXA1
HSPA1A
HSPA1B
HSPA1L
HSPA2
HSPA6
HSPA8
IL13RA2
IL24
IST1
ITIH5
KCTD6
KCTD7
KIF5B
KLK5
KLK7
KLK9
KRTAP13-1
KRTAP13-4
KRTAP4-12
KRTAP4-2
KRTAP4-4
KRTAP4-5
KRTAP6-3
LASP1
LRATD2
LYPD3
MAGED1
MEI4
MRC2
MTA3
MYOZ1
MYOZ3
MYPOP
NAT2
ODF1
ODF3L1
P4HA3
PDCD6
PDLIM2
PEF1
PGRMC2
PHF19
PLAC8
PPIL6
PPP1R32
PRDM14
PSMB5
PYCR3
RAMAC
RASL10B
RHOBTB2
RNF20
RPL22
RUNX1
SAMD4A
SAXO1
SCGB3A1
SH3RF2
SIAH1
SNRPB
SNRPC
SS18L1
SUOX
TBC1D3B
TBC1D3G
TBC1D7
TCL1B
TEKT5
TFAP2D
THRSP
TINAGL1
TLE5
TNFRSF1A
TNFRSF25
TRAPPC6A
TSG101
UNKL
USP22
VPS37C
ZBTB45
ZBTB5
ZIM2
292 interacting genes:
ADAM12
ADAMTSL4
AGXT
ALG13
ALPP
AMMECR1
AMOT
ANKS1A
ARID5A
ARMC7
ATG9B
ATP23
BAG4
BAHD1
BATF2
BHLHB9
BLCAP
BLZF1
BSCL2
BUD31
C11orf1
C11orf16
CATSPER1
CCDC120
CCDC33
CCN3
CCN4
CCN5
CCNK
CD164
CDPF1
CERCAM
CFP
CHIC2
CHRD
CHRDL2
CNFN
CNNM3
COL8A1
CREB5
CUTA
CXCL16
CYHR1
CYP21A2
CYSRT1
DOCK2
DOCK3
DOK3
DTX2
DUSP10
DUSP22
EFEMP1
EFEMP2
EGFL7
ENKD1
EPDR1
ESM1
ESR2
EVA1B
FAAP100
FAM219B
FAM221A
FBLN1
FHL3
FHL5
FOXH1
FOXN1
FRS3
FST
FUCA2
GAS8
GATA1
GCM2
GDF15
GNE
GP9
GPS2
GRN
GSTP1
GUCD1
HEXB
HEXIM2
HEY2
HOXB9
HR
HSD3B7
ID3
IGFL1
IGFN1
INCA1
INO80B
IRX6
ITGB4
KCTD9
KDM1A
KPRP
KRT31
KRT33B
KRT34
KRT35
KRT37
KRT38
KRT40
KRT81
KRT82
KRT83
KRTAP1-1
KRTAP1-3
KRTAP1-5
KRTAP10-1
KRTAP10-10
KRTAP10-11
KRTAP10-3
KRTAP10-4
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP11-1
KRTAP12-1
KRTAP12-2
KRTAP12-3
KRTAP12-4
KRTAP13-2
KRTAP13-3
KRTAP13-4
KRTAP15-1
KRTAP19-6
KRTAP19-7
KRTAP2-3
KRTAP2-4
KRTAP23-1
KRTAP26-1
KRTAP3-2
KRTAP3-3
KRTAP4-1
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-4
KRTAP4-5
KRTAP4-7
KRTAP5-11
KRTAP5-2
KRTAP5-3
KRTAP5-4
KRTAP5-6
KRTAP5-9
KRTAP6-1
KRTAP6-2
KRTAP6-3
KRTAP9-2
KRTAP9-3
KRTAP9-4
KRTAP9-8
LASP1
LCE1A
LCE1B
LCE1C
LCE1D
LCE1F
LCE2A
LCE2B
LCE2C
LCE2D
LCE3C
LCE3E
LCE4A
LCE5A
LGALS13
LGALS4
LMX1B
LNX1
LONRF1
LPXN
MACO1
MAPKBP1
MDFI
MFAP2
MGAT5B
MKRN3
MYO15B
MYPOP
N4BP2L2
NBPF19
NCK2
NECTIN2
NEDD9
NEK6
NELL2
NFKBID
NOTCH2NLA
NR1D2
NTN4
NXF1
ODF1
OIT3
P2RY6
PAX6
PBX2
PCSK5
PCYOX1
PHETA1
PIK3R1
PIN1
PITX1
PITX2
PKNOX1
PLEKHN1
PLLP
PLSCR1
PLSCR2
PLSCR3
PLSCR4
PPP1R32
PRICKLE4
PRMT6
PROP1
PSMB1
PTH1R
PVR
QARS1
RALGDS
RANBP3
RBCK1
RBP3
RBPMS
RCHY1
RGS17
RGS19
RGS20
RNF208
RSPO2
RTN4R
SCT
SDCBP
SIVA1
SLC15A3
SLC23A1
SLIT1
SLPI
SNRPB
SNRPC
SPATA12
SPATA18
SPRY1
SPRY2
SPRY3
SPRY4
SSC4D
SSUH2
STX11
SUV39H1
TBC1D10C
TBX15
TCF19
TCF3
TEKT4
TEKT5
TGFB1
TGM7
THAP7
TLE5
TNS2
TRAF1
TRAF2
TRAF4
TRAPPC6A
TRIM42
TRIM55
TRIM63
TRIM8
TRIP6
TSPAN4
UBL5
UNKL
VASN
VWC2
VWC2L
WDR83
WWOX
YIPF3
YPEL3
ZBTB16
ZIM2
ZMAT1
ZNF417
ZNF587
ZNF688
ZNF774
ZNF837
ZNF843
Entrez ID
9530
3198
HPRD ID
04861
00843
Ensembl ID
ENSG00000156735
ENSG00000105991
Uniprot IDs
O95429
P49639
PDB IDs
1M62
1M7K
Enriched GO Terms of Interacting Partners
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