TEKT5 and EPHB6

Data Source:
BioGRID (two hybrid)

		TEKT5	EPHB6
Description		tektin 5	EPH receptor B6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Microtubule Cytoskeleton Sperm Flagellum	Extracellular Region Cytosol Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection Receptor Complex
	Molecular Function	Protein Binding	Transmembrane Receptor Protein Tyrosine Kinase Activity Ephrin Receptor Activity Transmembrane-ephrin Receptor Activity ATP Binding Signaling Receptor Activity
	Biological Process	Cilium Assembly Cilium Movement Involved In Cell Motility	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organism Development Axon Guidance Peptidyl-tyrosine Phosphorylation Central Nervous System Projection Neuron Axonogenesis Positive Regulation Of Kinase Activity Ephrin Receptor Signaling Pathway
Pathways			EPH-Ephrin signaling EPH-Ephrin signaling EPHB-mediated forward signaling EPHB-mediated forward signaling Ephrin signaling Ephrin signaling EPH-ephrin mediated repulsion of cells
Drugs			Fostamatinib
Diseases
GWAS		Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Chronic obstructive pulmonary disease ( 30804561) Eating disorders ( 23568457) Lung adenocarcinoma ( 28604730) Lung function (FEV1/FVC) ( 26635082 30804560) Neonatal total 25-hydroxyvitamin D levels (maternal genetic effect) ( 32047095) Nickel levels ( 26025379) Normal facial asymmetry (angle of surface orientation score) ( 30631343) Peak expiratory flow ( 30804560) Resting heart rate ( 27798624)	Alcoholic chronic pancreatitis ( 28754779) Blood protein levels ( 30072576 29875488) Cancer ( 29299148)
Interacting Genes		46 interacting genes: AKAP8L BAG4 C19orf54 C7orf31 CABP2 CSKMT DTX2 EPHB6 EYA2 FNDC3B FOXH1 FOXI1 HGS HOXA1 HOXB6 KLHL38 KRTAP12-4 KRTAP15-1 KRTAP19-6 KRTAP19-7 KRTAP6-2 LASP1 MAPKBP1 MGAT5B NFKBID NHLRC2 PITX1 PLSCR4 PROP1 PSMB4 QRICH1 RBPMS RORB RUNX1 SMARCB1 SMUG1 SPAG8 SSC4D TBX15 TLX3 TNS2 TOX2 USP54 VENTX ZMYND12 ZNF76	27 interacting genes: AFDN ASB12 CBL CRK CRKL DDIT4L DUSP18 DUSP19 EFNB2 EPHB1 ERBB2 GRB2 HDHD2 INCA1 MSX2 MTARC1 NIF3L1 NOTCH2NLA POU6F2 PRMT5 REL SAT1 STYX TCF4 TEKT5 TRIB3 TRIM39
Entrez ID		146279	2051
HPRD ID		08736	04133
Ensembl ID		ENSG00000153060	ENSG00000106123
Uniprot IDs		Q96M29	F8WCM8 J3KQU5 O15197
PDB IDs
Enriched GO Terms of Interacting Partners?
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