LONRF1 and ZFP90

Data Source:
BioGRID (two hybrid)

		LONRF1	ZFP90
Description		LON peptidase N-terminal domain and ring finger 1	ZFP90 zinc finger protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Nucleus
	Molecular Function	Protein Binding Metal Ion Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	Protein Polyubiquitination	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA Binding Positive Regulation Of Transcription, DNA-templated
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Generic Transcription Pathway
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Colorectal cancer (diet interaction) ( 24743840) HDL cholesterol levels ( 32203549)	Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) HIV-1 viral setpoint ( 22174851) Response to antipsychotic treatment in schizophrenia (reasoning) ( 21107309) Systemic lupus erythematosus ( 27399966 28714469) Ulcerative colitis ( 28067908 23128233 21297633)
Interacting Genes		96 interacting genes: ADAMTSL4 ALAS1 AP2B1 ATG9A AVPI1 BHLHB9 BRCA1 BYSL C4orf17 CALCOCO2 CBLL2 CDKN2D CFP CRX CYSRT1 DVL3 EFHC2 FLACC1 GABPB2 GORASP1 GORASP2 HLX HOXA1 HSPB1 IHO1 IKZF2 IKZF3 IQCF2 KAT5 KATNBL1 KCTD21 KCTD9 KHDC1 KRT31 KRT35 KRT75 KRTAP1-3 KRTAP13-1 KRTAP13-3 KRTAP19-6 KRTAP19-7 KRTAP3-3 KRTAP6-1 LGALS9B LHX2 LHX4 LNX1 MAGED1 MGAT5B MID2 MRPL38 MTMR3 MYOZ3 NR4A1 NTAQ1 OOEP PATZ1 PAX5 PAX6 PAX8 PICK1 PLSCR1 POU6F2 PPP1R3C PRDM16 PRDM6 PRR35 PSMA1 RBPMS RIMBP3C RPRD1A SFN SLU7 SPRY2 STAU1 STX11 TASOR2 TBX19 TRAF2 TRIM27 TRIM42 TRIM8 TRIM9 UBE2I UBE2L6 UCHL3 USP2 VGLL1 WDR83 XIAP YPEL3 ZFP90 ZNF426 ZNF653 ZNF774 ZNHIT2	23 interacting genes: ABI2 ATPAF2 BOLA2 BOLA2B CCNC CPNE7 ENKD1 EXOSC5 GCC1 GLYCTK GTPBP3 HOXC8 LMO1 LONRF1 MALSU1 MLH1 NEK6 PRKAB2 RUNX1T1 TBC1D22B TDRKH TEKT4 TRAPPC6A
Entrez ID		91694	146198
HPRD ID		08674	18729
Ensembl ID		ENSG00000154359	ENSG00000184939
Uniprot IDs		Q17RB8	J3QKQ8 Q8TF47
PDB IDs
Enriched GO Terms of Interacting Partners?
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