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FOXH1 and PLA2G10
Data Source:
BioGRID
(two hybrid)
FOXH1
PLA2G10
Description
forkhead box H1
phospholipase A2 group X
Image
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Activin Responsive Factor Complex
Acrosomal Vesicle
Extracellular Region
Extracellular Space
Lysosome
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Protein Domain Specific Binding
BHLH Transcription Factor Binding
Sequence-specific DNA Binding
SMAD Binding
Androgen Receptor Binding
Co-SMAD Binding
R-SMAD Binding
1-alkyl-2-acetylglycerophosphocholine Esterase Activity
Phospholipase Activity
Phospholipase A2 Activity
Calcium Ion Binding
Protein Binding
Phospholipid Binding
Calcium-dependent Phospholipase A2 Activity
Phospholipase A2 Activity (consuming 1,2-dipalmitoylphosphatidylcholine)
Phospholipase A2 Activity Consuming 1,2-dioleoylphosphatidylethanolamine)
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Heart Looping
Secondary Heart Field Specification
Outflow Tract Morphogenesis
Cardiac Right Ventricle Morphogenesis
Ventricular Trabecula Myocardium Morphogenesis
Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway
Embryonic Heart Tube Anterior/posterior Pattern Specification
Aorta Morphogenesis
Negative Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Axial Mesoderm Development
Negative Regulation Of Androgen Receptor Signaling Pathway
Cellular Response To Cytokine Stimulus
Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry
Phospholipid Metabolic Process
Phosphatidic Acid Biosynthetic Process
Phosphatidylserine Metabolic Process
Axon Guidance
Positive Regulation Of Macrophage Derived Foam Cell Differentiation
Positive Regulation Of Lipid Storage
Arachidonic Acid Metabolic Process
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Prostaglandin Secretion
Low-density Lipoprotein Particle Remodeling
Phosphatidylcholine Catabolic Process
Phosphatidylglycerol Acyl-chain Remodeling
Phosphatidylinositol Acyl-chain Remodeling
Phosphatidylserine Acyl-chain Remodeling
Phosphatidylcholine Acyl-chain Remodeling
Phosphatidylethanolamine Acyl-chain Remodeling
Cholesterol Homeostasis
Regulation Of Macrophage Activation
Negative Regulation Of DNA-binding Transcription Factor Activity
Phosphatidylethanolamine Metabolic Process
Phosphatidylcholine Metabolic Process
Phosphatidylglycerol Metabolic Process
Phosphatidic Acid Metabolic Process
Arachidonic Acid Secretion
Defense Response To Virus
Lysophospholipid Transport
Platelet Activating Factor Catabolic Process
Positive Regulation Of Arachidonic Acid Secretion
Negative Regulation Of Cholesterol Efflux
Positive Regulation Of Acrosome Reaction
Pathways
Signaling by NODAL
Signaling by Activin
Acyl chain remodelling of PC
Acyl chain remodelling of PS
Acyl chain remodelling of PE
Acyl chain remodelling of PI
Acyl chain remodelling of PG
Synthesis of PA
Drugs
Varespladib methyl
Crotalus adamanteus antivenin
Agkistrodon piscivorus antivenin
Diseases
GWAS
Blood metabolite levels (
26401656
)
Educational attainment (
25201988
)
General cognitive ability (
29844566
)
Cholesteryl ester levels (
31551469
)
Glycerophospholipid levels (
26068415
)
Interacting Genes
67 interacting genes:
AOC1
ARID5A
ATP23
ATXN1L
BATF2
C10orf55
C11orf1
C19orf54
CEACAM6
CRX
CRYBA1
CYSRT1
DAZAP2
DRAP1
FAM168B
FAM83A
FOXD2
FOXG1
HDHD3
HEY1
HLX
HOXA1
HSF4
KLHL26
KRTAP11-1
KRTAP13-3
KRTAP19-2
KRTAP19-6
KRTAP19-7
KRTAP3-1
KRTAP3-3
KRTAP7-1
LASP1
MAGED1
MGAT5B
MSX2
NKX2-5
NOTO
OXER1
PLA2G10
PNMA5
PPP1R37
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PRR22
RBM46
RBPMS2
RNF144B
SERGEF
SMAD2
SMAD3
SMAD4
SOX14
SOX4
TEKT5
TFG
TLX3
TSC1
UBAP2
UFSP1
ZC3H10
ZIC1
ZNF34
ZNF503
49 interacting genes:
AGXT
AQP1
ARID5A
ATXN1
BAG3
BEX2
C1orf94
CATSPER1
CCDC120
CREB5
CYSRT1
FAM222B
FOXH1
GATA5
GNE
HGS
HOXC8
HR
HSF4
INCA1
KPRP
KRTAP11-1
KRTAP26-1
LCE1A
LCE1C
LCE2A
LCE2B
LCE2D
MAL
MAPKBP1
MGAT5B
MYO10
NOXA1
NTAQ1
OTX1
PITX1
PLA2R1
POU4F3
PPP1R32
ROR2
SNRPC
SPAG8
STK16
TBX6
TFG
TLX3
VGLL3
VPS37C
ZC3H10
Entrez ID
8928
8399
HPRD ID
04689
04674
Ensembl ID
ENSG00000160973
ENSG00000069764
Uniprot IDs
O75593
O15496
PDB IDs
5XOC
1LE6
1LE7
4UY1
5G3M
5OW8
5OWC
6G5J
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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