NIP7 and ZBED1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NIP7	ZBED1
Description		nucleolar pre-rRNA processing protein NIP7	zinc finger BED-type containing 1
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GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytosol Preribosome, Large Subunit Precursor	Chromatin Nucleus Nucleoplasm Centrosome PML Body Nuclear Membrane
	Molecular Function	RNA Binding Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding SUMO Transferase Activity Identical Protein Binding Sequence-specific DNA Binding Metal Ion Binding Protein Dimerization Activity SUMO Ligase Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Ribosome Assembly Ribosomal Large Subunit Biogenesis	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Viral Process Negative Regulation By Host Of Viral Genome Replication Positive Regulation Of Transcription By RNA Polymerase II Protein Autosumoylation
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol	SUMOylation of chromatin organization proteins
Drugs		Radezolid
Diseases
GWAS		Body mass index ( 26426971) Logical memory (delayed recall) in normal cognition ( 29274321)
Interacting Genes		5 interacting genes: CRX LZTS2 NECAB2 NOL8 ZBED1	55 interacting genes: AMOTL2 ATRX C1orf109 CCDC13 CDC37 CTNNAL1 DGCR6 EFHC1 FABP4 FAM124B FANCG FNDC11 GGACT GORASP2 GPN1 GPSM1 KDM1A KIFC3 KLHL40 LCN2 LNX1 LRRC20 MAD2L2 MAGEB2 MKKS MLH1 MPST MYO15B NCDN NIF3L1 NIP7 NTAQ1 NUDT18 PAX6 PIAS2 PICK1 POLE2 POLR1C PRKAA1 PRKAR1A PSAP RENBP RIN1 SORBS3 SPEF1 SSX2 SUMO2 TRAPPC2 TRAPPC2B TRIML2 TTC23 TTR UBE2I UCHL5 USP2
Entrez ID		51388	9189
HPRD ID		16709	02170
Ensembl ID		ENSG00000132603	ENSG00000214717
Uniprot IDs		Q9Y221	A0A024RBU4 O96006
PDB IDs		1SQW 1T5Y	2CT5
Enriched GO Terms of Interacting Partners?
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