Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
ATF2 and MAPK9
Data Source:
HPRD
(in vitro)
ATF2
MAPK9
Description
activating transcription factor 2
mitogen-activated protein kinase 9
Image
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrial Outer Membrane
Site Of Double-strand Break
H4 Histone Acetyltransferase Complex
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrion
Cytosol
Molecular Function
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Cis-regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Activating Transcription Factor Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Chromatin Binding
DNA-binding Transcription Factor Activity
Histone Acetyltransferase Activity
Protein Binding
CAMP Response Element Binding Protein Binding
H4 Histone Acetyltransferase Activity
Protein Kinase Binding
CAMP Response Element Binding
H2B Histone Acetyltransferase Activity
Protein-containing Complex Binding
Metal Ion Binding
Sequence-specific Double-stranded DNA Binding
Protein Serine/threonine Kinase Activity
JUN Kinase Activity
MAP Kinase Activity
Protein Serine/threonine/tyrosine Kinase Activity
Protein Binding
ATP Binding
Transcription Factor Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Outflow Tract Morphogenesis
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Response To Osmotic Stress
Cellular Response To DNA Damage Stimulus
Response To Water Deprivation
Positive Regulation Of Gene Expression
Negative Regulation Of Angiogenesis
Intra-S DNA Damage Checkpoint
Positive Regulation Of Transforming Growth Factor Beta2 Production
Positive Regulation Of Neuron Apoptotic Process
Histone H4 Acetylation
Histone H2B Acetylation
Fat Cell Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Epithelial Cell Proliferation
Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of DNA-binding Transcription Factor Activity
Adipose Tissue Development
Amelogenesis
Positive Regulation Of Cardiac Muscle Myoblast Proliferation
Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process
Protein Phosphorylation
JNK Cascade
JUN Phosphorylation
Positive Regulation Of Gene Expression
Positive Regulation Of Macrophage Derived Foam Cell Differentiation
Peptidyl-serine Phosphorylation
Positive Regulation Of Protein Ubiquitination
Cellular Response To Reactive Oxygen Species
Intracellular Signal Transduction
Fc-epsilon Receptor Signaling Pathway
Regulation Of Circadian Rhythm
Rhythmic Process
Regulation Of DNA-binding Transcription Factor Activity
Protein Localization To Tricellular Tight Junction
Cellular Response To Cadmium Ion
Positive Regulation Of Podosome Assembly
Positive Regulation Of Transcription Factor Catabolic Process
Positive Regulation Of Apoptotic Signaling Pathway
Pathways
Transcriptional activation of mitochondrial biogenesis
HATs acetylate histones
Circadian Clock
Activation of the AP-1 family of transcription factors
TP53 Regulates Transcription of DNA Repair Genes
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Estrogen-dependent gene expression
NGF-stimulated transcription
NGF-stimulated transcription
Response of EIF2AK4 (GCN2) to amino acid deficiency
Response of EIF2AK4 (GCN2) to amino acid deficiency
Oxidative Stress Induced Senescence
FCERI mediated MAPK activation
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
Activation of the AP-1 family of transcription factors
Drugs
Pseudoephedrine
Minocycline
N-{3-[5-(1H-1,2,4-triazol-3-yl)-1H-indazol-3-yl]phenyl}furan-2-carboxamide
Fostamatinib
Halicin
Diseases
GWAS
Intake of total sugars (
31005972
)
Metabolite levels (
23823483
)
Blood protein levels (
30072576
)
Interacting Genes
63 interacting genes:
APP
AR
ATF3
ATF4
ATF7
BACH1
BANP
BATF
CCDC6
CCND1
CEBPA
CEBPB
CEBPG
CENPQ
CREB5
CSNK2A1
CSNK2A2
DDIT3
DNMT3L
EDF1
ETS1
EXOSC8
FOS
FOSB
FOSL1
FOSL2
GTF2F2
H2BC21
HMGA1
IRF2BP1
JDP2
JUN
KIFC3
LHX8
MACROH2A1
MAPK1
MAPK10
MAPK11
MAPK13
MAPK14
MAPK8
MAPK9
MAPKAPK5
MLH1
NBN
NCOA6
PIAS2
PML
PRKCE
RB1
RNF4
RPS6KA5
RUVBL2
SMAD3
SMAD4
SPOPL
SRA1
SUMO1
THRB
UBE2I
UTF1
XPO1
YY1
112 interacting genes:
ACP5
AKT1
ARRB1
ARRB2
ATF2
ATF7
BCL2L1
BCL2L11
BNIP5
C1orf105
C1orf94
CASP3
CBLL2
CCDC33
CDC16
CDC25B
CDC25C
CEP126
CEP44
CLU
CTBP1
CTNNB1
CYHR1
DCX
DTX3
DUSP10
DUSP16
DUSP19
DUSP4
EEF2K
EFHC2
EGFR
ELK1
ELK3
ENKD1
FBXO7
GFAP
GOLGA6A
GRB2
GSC2
H3-3A
HDAC9
HSF1
IHO1
IRS1
ITGB3BP
JDP2
JUN
JUNB
JUND
KLHL8
KPNA3
L3MBTL3
LHX3
LMAN2
LNX1
LNX2
LZTS1
MACF1
MAP2K4
MAP2K7
MAP3K1
MAP3K10
MAPK8IP1
MAPK8IP2
MAPK8IP3
MAPKAPK5
MAPKBP1
MAPT
MCRS1
MED12L
MEOX1
MLIP
NCF1
NCSTN
NFATC3
NFATC4
NHSL2
PAX5
PBX4
PICK1
POU6F2
PPARG
PRKD1
PSEN1
RASL10B
RB1
RPS6KB1
RSPO4
SAXO1
SDCBP
SF3B4
SH3BP5
SHMT1
SMAD2
SMAD3
SMCO3
SSU72
TCP10L
TEX11
TOB1
TP53
TRAF2
TUSC2
WDR62
XPNPEP1
XPO7
ZBTB25
ZC2HC1C
ZNF138
ZNF559
ZNHIT1
Entrez ID
1386
5601
HPRD ID
00443
04206
Ensembl ID
ENSG00000115966
ENSG00000050748
Uniprot IDs
A4D7V5
P15336
D7R525
D7R526
P45984
PDB IDs
1BHI
1T2K
4H36
3E7O
3NPC
7CML
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?