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MAPK9 and CYHR1
Data Source:
BioGRID
(two hybrid)
MAPK9
CYHR1
Description
mitogen-activated protein kinase 9
cysteine and histidine rich 1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrion
Cytosol
Nucleoplasm
Perinuclear Region Of Cytoplasm
Molecular Function
Protein Serine/threonine Kinase Activity
JUN Kinase Activity
MAP Kinase Activity
Protein Serine/threonine/tyrosine Kinase Activity
Protein Binding
ATP Binding
Transcription Factor Binding
Protein Binding
Zinc Ion Binding
Biological Process
Protein Phosphorylation
JNK Cascade
JUN Phosphorylation
Positive Regulation Of Gene Expression
Positive Regulation Of Macrophage Derived Foam Cell Differentiation
Peptidyl-serine Phosphorylation
Positive Regulation Of Protein Ubiquitination
Cellular Response To Reactive Oxygen Species
Intracellular Signal Transduction
Fc-epsilon Receptor Signaling Pathway
Regulation Of Circadian Rhythm
Rhythmic Process
Regulation Of DNA-binding Transcription Factor Activity
Protein Localization To Tricellular Tight Junction
Cellular Response To Cadmium Ion
Positive Regulation Of Podosome Assembly
Positive Regulation Of Transcription Factor Catabolic Process
Positive Regulation Of Apoptotic Signaling Pathway
Pathways
Oxidative Stress Induced Senescence
FCERI mediated MAPK activation
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
Activation of the AP-1 family of transcription factors
Drugs
Minocycline
N-{3-[5-(1H-1,2,4-triazol-3-yl)-1H-indazol-3-yl]phenyl}furan-2-carboxamide
Fostamatinib
Halicin
Diseases
GWAS
Blood protein levels (
30072576
)
Age at first birth (
27798627
)
Blood metabolite levels (
26401656
)
Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) (
31374203
)
Educational attainment (
25201988
)
General cognitive ability (
29844566
)
Interacting Genes
112 interacting genes:
ACP5
AKT1
ARRB1
ARRB2
ATF2
ATF7
BCL2L1
BCL2L11
BNIP5
C1orf105
C1orf94
CASP3
CBLL2
CCDC33
CDC16
CDC25B
CDC25C
CEP126
CEP44
CLU
CTBP1
CTNNB1
CYHR1
DCX
DTX3
DUSP10
DUSP16
DUSP19
DUSP4
EEF2K
EFHC2
EGFR
ELK1
ELK3
ENKD1
FBXO7
GFAP
GOLGA6A
GRB2
GSC2
H3-3A
HDAC9
HSF1
IHO1
IRS1
ITGB3BP
JDP2
JUN
JUNB
JUND
KLHL8
KPNA3
L3MBTL3
LHX3
LMAN2
LNX1
LNX2
LZTS1
MACF1
MAP2K4
MAP2K7
MAP3K1
MAP3K10
MAPK8IP1
MAPK8IP2
MAPK8IP3
MAPKAPK5
MAPKBP1
MAPT
MCRS1
MED12L
MEOX1
MLIP
NCF1
NCSTN
NFATC3
NFATC4
NHSL2
PAX5
PBX4
PICK1
POU6F2
PPARG
PRKD1
PSEN1
RASL10B
RB1
RPS6KB1
RSPO4
SAXO1
SDCBP
SF3B4
SH3BP5
SHMT1
SMAD2
SMAD3
SMCO3
SSU72
TCP10L
TEX11
TOB1
TP53
TRAF2
TUSC2
WDR62
XPNPEP1
XPO7
ZBTB25
ZC2HC1C
ZNF138
ZNF559
ZNHIT1
12 interacting genes:
ALDH3A1
HOXA1
KPNA3
KPNA4
KRTAP1-1
KRTAP1-3
LGALS3
MAPK9
NBPF19
NOTCH2NLA
PVR
SDCBP
Entrez ID
5601
50626
HPRD ID
04206
13107
Ensembl ID
ENSG00000050748
ENSG00000187954
Uniprot IDs
D7R525
D7R526
P45984
E9PJD7
Q6ZMK1
PDB IDs
3E7O
3NPC
7CML
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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