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MAPK9 and MEOX1
Data Source:
BioGRID
(two hybrid, two hybrid)
MAPK9
MEOX1
Description
mitogen-activated protein kinase 9
mesenchyme homeobox 1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrion
Cytosol
Chromatin
Nucleus
Cytoplasm
Molecular Function
Protein Serine/threonine Kinase Activity
JUN Kinase Activity
MAP Kinase Activity
Protein Serine/threonine/tyrosine Kinase Activity
Protein Binding
ATP Binding
Transcription Factor Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Chromatin Binding
DNA-binding Transcription Factor Activity
Protein Binding
Sequence-specific DNA Binding
HMG Box Domain Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Protein Phosphorylation
JNK Cascade
JUN Phosphorylation
Positive Regulation Of Gene Expression
Positive Regulation Of Macrophage Derived Foam Cell Differentiation
Peptidyl-serine Phosphorylation
Positive Regulation Of Protein Ubiquitination
Cellular Response To Reactive Oxygen Species
Intracellular Signal Transduction
Fc-epsilon Receptor Signaling Pathway
Regulation Of Circadian Rhythm
Rhythmic Process
Regulation Of DNA-binding Transcription Factor Activity
Protein Localization To Tricellular Tight Junction
Cellular Response To Cadmium Ion
Positive Regulation Of Podosome Assembly
Positive Regulation Of Transcription Factor Catabolic Process
Positive Regulation Of Apoptotic Signaling Pathway
Somite Specification
Regulation Of Transcription By RNA Polymerase II
Multicellular Organism Development
Biological_process
Positive Regulation Of Transcription By RNA Polymerase II
Hematopoietic Stem Cell Differentiation
Somite Development
Sclerotome Development
Pathways
Oxidative Stress Induced Senescence
FCERI mediated MAPK activation
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
Activation of the AP-1 family of transcription factors
Drugs
Minocycline
N-{3-[5-(1H-1,2,4-triazol-3-yl)-1H-indazol-3-yl]phenyl}furan-2-carboxamide
Fostamatinib
Halicin
Diseases
GWAS
Blood protein levels (
30072576
)
Fractures (
30158200
)
Interacting Genes
112 interacting genes:
ACP5
AKT1
ARRB1
ARRB2
ATF2
ATF7
BCL2L1
BCL2L11
BNIP5
C1orf105
C1orf94
CASP3
CBLL2
CCDC33
CDC16
CDC25B
CDC25C
CEP126
CEP44
CLU
CTBP1
CTNNB1
CYHR1
DCX
DTX3
DUSP10
DUSP16
DUSP19
DUSP4
EEF2K
EFHC2
EGFR
ELK1
ELK3
ENKD1
FBXO7
GFAP
GOLGA6A
GRB2
GSC2
H3-3A
HDAC9
HSF1
IHO1
IRS1
ITGB3BP
JDP2
JUN
JUNB
JUND
KLHL8
KPNA3
L3MBTL3
LHX3
LMAN2
LNX1
LNX2
LZTS1
MACF1
MAP2K4
MAP2K7
MAP3K1
MAP3K10
MAPK8IP1
MAPK8IP2
MAPK8IP3
MAPKAPK5
MAPKBP1
MAPT
MCRS1
MED12L
MEOX1
MLIP
NCF1
NCSTN
NFATC3
NFATC4
NHSL2
PAX5
PBX4
PICK1
POU6F2
PPARG
PRKD1
PSEN1
RASL10B
RB1
RPS6KB1
RSPO4
SAXO1
SDCBP
SF3B4
SH3BP5
SHMT1
SMAD2
SMAD3
SMCO3
SSU72
TCP10L
TEX11
TOB1
TP53
TRAF2
TUSC2
WDR62
XPNPEP1
XPO7
ZBTB25
ZC2HC1C
ZNF138
ZNF559
ZNHIT1
99 interacting genes:
ACBD4
ACOT12
ALOX5
ANAPC2
APP
APPL1
ATG9A
BANP
BNIP2
BYSL
C14orf119
C1orf109
C1orf50
C2CD6
CACNB3
CCDC102B
CCDC103
CDC34
CIAO1
CIB3
CKS1B
CNOT11
CSNK2A1
CWF19L2
CYFIP1
DCX
DUSP3
EIF4A3
EIF4EBP1
EMD
FAM126B
FMR1
GCC1
GEMIN2
GPANK1
GYS1
HMBOX1
HMGB3
HOMER3
HOXC8
INPP5J
KANK2
KCTD7
L3MBTL2
LMNA
MAPK9
MBD3
MCRS1
MEF2A
MID1
MID2
MKRN3
MLX
MORF4L1
MVP
NAGK
NDOR1
NEIL2
OSGIN1
PAGE3
PARVG
PAX1
PAX3
PCP2
PDE4C
PELI2
PIN1
PLCD4
PM20D2
POLR3GL
PPM1F
PRKAG1
PRKN
QRICH1
RAD52
RANBP3
RBM41
RBM5
SDCBP
SEC14L4
SOX10
SPAG8
SPIC
SYT17
TCEANC
TCP11L1
TEX33
TRAPPC2L
TRIM41
TRIML2
TRIP10
TXLNA
TXNL4B
UBE2R2
UBXN2B
UBXN7
UNC45A
ZCCHC10
ZNF410
Entrez ID
5601
4222
HPRD ID
04206
02537
Ensembl ID
ENSG00000050748
ENSG00000005102
Uniprot IDs
D7R525
D7R526
P45984
P50221
PDB IDs
3E7O
3NPC
7CML
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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