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MAPK9 and CEP126
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
MAPK9
CEP126
Description
mitogen-activated protein kinase 9
centrosomal protein 126
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrion
Cytosol
Cytoplasm
Centrosome
Midbody
Ciliary Base
Molecular Function
Protein Serine/threonine Kinase Activity
JUN Kinase Activity
MAP Kinase Activity
Protein Serine/threonine/tyrosine Kinase Activity
Protein Binding
ATP Binding
Transcription Factor Binding
Protein Binding
Biological Process
Protein Phosphorylation
JNK Cascade
JUN Phosphorylation
Positive Regulation Of Gene Expression
Positive Regulation Of Macrophage Derived Foam Cell Differentiation
Peptidyl-serine Phosphorylation
Positive Regulation Of Protein Ubiquitination
Cellular Response To Reactive Oxygen Species
Intracellular Signal Transduction
Fc-epsilon Receptor Signaling Pathway
Regulation Of Circadian Rhythm
Rhythmic Process
Regulation Of DNA-binding Transcription Factor Activity
Protein Localization To Tricellular Tight Junction
Cellular Response To Cadmium Ion
Positive Regulation Of Podosome Assembly
Positive Regulation Of Transcription Factor Catabolic Process
Positive Regulation Of Apoptotic Signaling Pathway
Mitotic Spindle Organization
Cytoplasmic Microtubule Organization
Cilium Assembly
Non-motile Cilium Assembly
Pathways
Oxidative Stress Induced Senescence
FCERI mediated MAPK activation
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
Activation of the AP-1 family of transcription factors
Drugs
Minocycline
N-{3-[5-(1H-1,2,4-triazol-3-yl)-1H-indazol-3-yl]phenyl}furan-2-carboxamide
Fostamatinib
Halicin
Diseases
GWAS
Blood protein levels (
30072576
)
Interacting Genes
112 interacting genes:
ACP5
AKT1
ARRB1
ARRB2
ATF2
ATF7
BCL2L1
BCL2L11
BNIP5
C1orf105
C1orf94
CASP3
CBLL2
CCDC33
CDC16
CDC25B
CDC25C
CEP126
CEP44
CLU
CTBP1
CTNNB1
CYHR1
DCX
DTX3
DUSP10
DUSP16
DUSP19
DUSP4
EEF2K
EFHC2
EGFR
ELK1
ELK3
ENKD1
FBXO7
GFAP
GOLGA6A
GRB2
GSC2
H3-3A
HDAC9
HSF1
IHO1
IRS1
ITGB3BP
JDP2
JUN
JUNB
JUND
KLHL8
KPNA3
L3MBTL3
LHX3
LMAN2
LNX1
LNX2
LZTS1
MACF1
MAP2K4
MAP2K7
MAP3K1
MAP3K10
MAPK8IP1
MAPK8IP2
MAPK8IP3
MAPKAPK5
MAPKBP1
MAPT
MCRS1
MED12L
MEOX1
MLIP
NCF1
NCSTN
NFATC3
NFATC4
NHSL2
PAX5
PBX4
PICK1
POU6F2
PPARG
PRKD1
PSEN1
RASL10B
RB1
RPS6KB1
RSPO4
SAXO1
SDCBP
SF3B4
SH3BP5
SHMT1
SMAD2
SMAD3
SMCO3
SSU72
TCP10L
TEX11
TOB1
TP53
TRAF2
TUSC2
WDR62
XPNPEP1
XPO7
ZBTB25
ZC2HC1C
ZNF138
ZNF559
ZNHIT1
87 interacting genes:
AIMP2
AKTIP
ARIH2
ATP6V1F
ATRX
BMI1
BRD1
C11orf58
CDKN2B
CRCT1
CSTF2
DGCR6
DISC1
DLEU1
DNM1
DUSP12
DUSP23
EIF2S2
EIF6
EPN1
FAM118B
FEZ1
FGFR3
FXR1
GEMIN7
GET4
GIT1
GOLGB1
GPRASP2
GSTO1
HMOX2
HTT
ING5
KAT5
KAT7
KIF15
KLHL20
LAMTOR5
LPL
LRRC1
LUC7L2
MAD2L1BP
MAPK9
MLH1
MRPS6
NAP1L5
NAT9
NPM3
NSF
NUDT21
ODF2L
OFD1
PBK
PDCD5
PFDN1
PIK3R3
PMF1
POLD1
POLR2M
PPP1CA
PPP1CC
PRKRA
PTPRS
RAB27A
RAN
RBM23
RETREG2
RGS2
RIF1
ROGDI
RPA2
RUVBL1
SAT1
SNRPG
SPDL1
STAU2
TFG
TNFRSF14
TNFSF11
TOMM20
TTR
TXNDC9
VIM
YAE1
YWHAZ
ZBED8
ZNF24
Entrez ID
5601
57562
HPRD ID
04206
17212
Ensembl ID
ENSG00000050748
ENSG00000110318
Uniprot IDs
D7R525
D7R526
P45984
Q9P2H0
PDB IDs
3E7O
3NPC
7CML
Enriched GO Terms of Interacting Partners
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