TMEM42 and RHBDD1

Data Source:
BioGRID (two hybrid)

		TMEM42	RHBDD1
Description		transmembrane protein 42	rhomboid domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane Mitochondrial Membrane Endoplasmic Reticulum Quality Control Compartment
	Molecular Function	Protein Binding	Serine-type Endopeptidase Activity Protein Binding
	Biological Process		Apoptotic Process Positive Regulation Of Protein Processing Membrane Protein Intracellular Domain Proteolysis Cellular Response To Unfolded Protein Cellular Response To UV ERAD Pathway Negative Regulation Of Apoptotic Process Post-translational Protein Modification Spermatid Differentiation Membrane Protein Proteolysis Involved In Retrograde Protein Transport, ER To Cytosol Regulation Of Male Germ Cell Proliferation
Pathways
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Bipolar disorder ( 31043756)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Pulmonary function ( 17903307)
Interacting Genes		54 interacting genes: AQP3 AQP6 BDKRB1 CD79A DTX2 EBP EDA ELOVL4 ERGIC3 FAM174A FAM209A GET1 GJA8 GOLM2 GPR152 GPX8 HSD17B11 HSD17B13 LEPROTL1 LHFPL5 LMNA MFF MGAT5B MMD MMGT1 MRM1 MTIF3 NEMP1 PROP1 PSCA RABAC1 RBPMS REEP1 REEP2 RETREG3 RHBDD1 SAR1A SCN3B SEC11C SERINC2 SHISAL1 SLC18A1 SLC34A2 SMIM14 SVOPL TLX3 TM4SF19 TMEM147 TMEM14B TMEM237 TMEM35A TMEM74 VENTX ZDHHC15	18 interacting genes: CGRRF1 CMTM5 CREB3L1 CTSA DAPK1 FBXO25 GYPC LPCAT2 LRRK2 MFHAS1 NSDHL PLEKHB2 RNF5 SEC22B SLC66A2 TMEM42 TMEM86B TMIE
Entrez ID		131616	84236
HPRD ID		15540	13206
Ensembl ID		ENSG00000169964	ENSG00000144468
Uniprot IDs		Q69YG0	Q8TEB9
PDB IDs			5EPP
Enriched GO Terms of Interacting Partners?
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