TMEM42 and SLC34A2

Data Source:
BioGRID (two hybrid)

		TMEM42	SLC34A2
Description		transmembrane protein 42	solute carrier family 34 member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Brush Border Integral Component Of Membrane Apical Plasma Membrane Brush Border Membrane Vesicle
	Molecular Function	Protein Binding	Sodium:phosphate Symporter Activity Sodium Ion Binding Phosphate Ion Binding
	Biological Process		In Utero Embryonic Development Phosphate Ion Transport Cellular Phosphate Ion Homeostasis Sodium Ion Transmembrane Transport Response To Estrogen Cellular Protein Metabolic Process Sodium-dependent Phosphate Transport
Pathways			Type II Na+/Pi cotransporters Defective SLC34A2 causes pulmonary alveolar microlithiasis (PALM) Surfactant metabolism Defective SLC34A2 causes PALM
Drugs
Diseases			Non-small cell lung cancer
GWAS		Acne (severe) ( 24927181) Bipolar disorder ( 31043756)	Metabolite levels ( 23823483)
Interacting Genes		54 interacting genes: AQP3 AQP6 BDKRB1 CD79A DTX2 EBP EDA ELOVL4 ERGIC3 FAM174A FAM209A GET1 GJA8 GOLM2 GPR152 GPX8 HSD17B11 HSD17B13 LEPROTL1 LHFPL5 LMNA MFF MGAT5B MMD MMGT1 MRM1 MTIF3 NEMP1 PROP1 PSCA RABAC1 RBPMS REEP1 REEP2 RETREG3 RHBDD1 SAR1A SCN3B SEC11C SERINC2 SHISAL1 SLC18A1 SLC34A2 SMIM14 SVOPL TLX3 TM4SF19 TMEM147 TMEM14B TMEM237 TMEM35A TMEM74 VENTX ZDHHC15	19 interacting genes: AIG1 ERG28 FXYD6-FXYD2 GUCA2A JAGN1 LHFPL5 PLN PNLIPRP1 RTP2 SLC30A3 SLC35A1 SLC39A7 STRIT1 TEX264 TMEM128 TMEM239 TMEM42 TRARG1 TSPO2
Entrez ID		131616	10568
HPRD ID		15540	07251
Ensembl ID		ENSG00000169964	ENSG00000157765
Uniprot IDs		Q69YG0	O95436
PDB IDs
Enriched GO Terms of Interacting Partners?
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