RHBDD1 and CGRRF1

Data Source:
BioGRID (two hybrid)

		RHBDD1	CGRRF1
Description		rhomboid domain containing 1	cell growth regulator with ring finger domain 1
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane Mitochondrial Membrane Endoplasmic Reticulum Quality Control Compartment	Nucleoplasm Endoplasmic Reticulum Intracellular Membrane-bounded Organelle
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding	Protein Binding Metal Ion Binding
	Biological Process	Apoptotic Process Positive Regulation Of Protein Processing Membrane Protein Intracellular Domain Proteolysis Cellular Response To Unfolded Protein Cellular Response To UV ERAD Pathway Negative Regulation Of Apoptotic Process Post-translational Protein Modification Spermatid Differentiation Membrane Protein Proteolysis Involved In Retrograde Protein Transport, ER To Cytosol Regulation Of Male Germ Cell Proliferation	Cell Cycle Arrest Negative Regulation Of Cell Population Proliferation Negative Regulation Of Cell Growth
Pathways
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Pulmonary function ( 17903307)	Dental caries ( 23259602) Monobrow thickness ( 26926045) Night sleep phenotypes ( 27126917)
Interacting Genes		18 interacting genes: CGRRF1 CMTM5 CREB3L1 CTSA DAPK1 FBXO25 GYPC LPCAT2 LRRK2 MFHAS1 NSDHL PLEKHB2 RNF5 SEC22B SLC66A2 TMEM42 TMEM86B TMIE	32 interacting genes: AGR3 BET1 CD72 CDIPT CREB3 CYB5B FAM241B FAXDC2 FFAR2 GPR151 GPR152 JAGN1 KLRC1 LAPTM4B LNPEP MARCHF5 MTIF3 PEX10 PGAP2 RHBDD1 SCAMP4 SLC30A3 SLC30A8 SUSD3 TMEM140 TMEM187 TMEM31 TMEM97 TPRG1 UBE2U YIPF6 ZFPL1
Entrez ID		84236	10668
HPRD ID		13206	09366
Ensembl ID		ENSG00000144468	ENSG00000100532
Uniprot IDs		Q8TEB9	Q99675
PDB IDs		5EPP	2EA5
Enriched GO Terms of Interacting Partners?
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