NTAN1 and UBR1

Data Source:
BioGRID (two hybrid)

		NTAN1	UBR1
Description		N-terminal asparagine amidase	ubiquitin protein ligase E3 component n-recognin 1
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GO Annotations	Cellular Component	Nucleus Cytoplasm	Ubiquitin Ligase Complex Proteasome Complex Cytoplasm Cytosol
	Molecular Function	Protein Binding Protein-N-terminal Asparagine Amidohydrolase Activity	Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity Leucine Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process	Protein Ubiquitination Negative Regulation Of TOR Signaling Cellular Response To Leucine Ubiquitin-dependent Protein Catabolic Process Via The N-end Rule Pathway
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases			Johanson-Blizzard syndrome
GWAS		Appendicular lean mass ( 33097823) Body mass index ( 29273807) Femoral neck bone mineral density ( 22504420) Fruit consumption ( 32066663) Glycerophospholipid levels ( 26068415) Height ( 31562340 20189936) Metabolite levels ( 23823483) Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) ( 24823311) Serum metabolite ratios in chronic kidney disease ( 29545352) Weight ( 28552196)	MGMT methylation in smokers ( 26183928) Triglycerides ( 25961943)
Interacting Genes		5 interacting genes: ATE1 MEOX2 NTAQ1 UBR1 UBR2	28 interacting genes: ANXA3 ARL15 ARL3 ARL4D BCL2L1 BTBD2 CDC42 CDC6 DLEU1 DNAJB11 FOS FTH1 GADD45A GSK3B LAMA4 LAMTOR3 NDUFA4L2 NTAN1 NTAQ1 NUDT3 PTPRS SERPINB9 SPRY2 TAC3 TP53I3 UBE2A UBE2B UBE2D2
Entrez ID		123803	197131
HPRD ID		17649	09342
Ensembl ID		ENSG00000157045	ENSG00000159459
Uniprot IDs		A0A087X0T5 Q96AB6	Q8IWV7
PDB IDs		6A0E 6A0F 6A0H 6A0I	3NY1 5TDC
Enriched GO Terms of Interacting Partners?
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