SSX2IP and TOP3B

Data Source:
BioGRID (two hybrid)

		SSX2IP	TOP3B
Description		SSX family member 2 interacting protein	DNA topoisomerase III beta
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Adherens Junction Cell Leading Edge Protein-containing Complex Centriolar Satellite Ciliary Basal Body	Condensed Chromosome Nucleus
	Molecular Function	Protein Binding Protein Domain Specific Binding	DNA Binding RNA Binding DNA Topoisomerase Activity DNA Topoisomerase Type I (single Strand Cut, ATP-independent) Activity Protein Binding
	Biological Process	Centrosome Cycle Cell Adhesion Regulation Of Rac Protein Signal Transduction Intraciliary Transport Involved In Cilium Assembly Cilium Assembly Regulation Of Cell Motility	DNA Topological Change Chromosome Segregation
Pathways
Drugs
Diseases
GWAS		Urinary albumin-to-creatinine ratio in non-diabetics ( 26631737) Waist-to-hip ratio adjusted for body mass index ( 28430825)	Attention function in attention deficit hyperactive disorder ( 26174813) Bipolar disorder ( 31043756) Diastolic blood pressure ( 29208002) Response to selective serotonin reuptake inhibitors in depression ( 27622933)
Interacting Genes		113 interacting genes: ABLIM3 ACTN1 ACTN2 AEN AFDN AP1M1 ARNT2 BCL6 BEX2 BRCA1 BYSL C11orf54 CARD9 CCDC187 CCDC198 CCHCR1 CCNH CDC23 CDC42 CDCA7L CHCHD3 DAXX DRG1 DVL2 EAF2 EHHADH EIF4A2 ERAL1 FAM124B FAM161A FAM214A FANCG FANCL FBF1 FNDC11 FRMD6 GEM GOLGA2 GOLGA8F GRAP2 HDAC4 HNRNPLL IKBKG INO80B KAT5 KDM1A KIF9 KIFC3 KLHL42 KRT15 KRT31 KRT40 KRTAP10-7 LATS1 LMO2 MCM7 MFAP1 MORN4 MOS MRPL53 NAA10 NDN NIF3L1 NOL12 NTAQ1 PHC2 PIMREG PKN1 PNMA1 POLL PRKAA1 PRKAB2 PRMT6 PRPF3 PRPF31 PSMA1 RNF6 SCNM1 SHFL SSX2 SSX3 SYT17 TBP TEAD4 TFIP11 TOP3B TRIM42 TRIM54 TSGA10IP TSTD2 TTC23 WDR5 XIAP YWHAQ YWHAZ ZBTB24 ZFYVE26 ZGPAT ZMAT2 ZNF124 ZNF202 ZNF250 ZNF3 ZNF408 ZNF417 ZNF438 ZNF587 ZNF648 ZNF688 ZNF71 ZNF792 ZRSR2 ZSCAN12	24 interacting genes: ADAMTSL4 AXIN2 BHLHB9 C1QBP CENPF CHD8 CHIC2 CIAO1 FASTK FBLN5 GRN KANK2 KRTAP4-12 MID2 PNMA2 RECQL5 SNRPB SPRED2 SSX2IP TRIM41 UPF2 ZFPM1 ZNF250 ZNF408
Entrez ID		117178	8940
HPRD ID		10566	04662
Ensembl ID		ENSG00000117155	ENSG00000100038
Uniprot IDs		B7ZB07 Q9Y2D8	A0A024R1C2 A8K4N2 O95985
PDB IDs			5GVC 5GVE
Enriched GO Terms of Interacting Partners?
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